Eating disorders in adolescents and young adults with cystic fibrosis.

Autor: Kass AP; Division of Pediatric Pulmonology, Columbia University Irving Medical Center, New York City, New York, USA., Berbert L; Boston Children's Hospital, Boston, Massachusetts, USA., Dahlberg S; Division of Pulmonary Medicine, Boston, Massachusetts, USA., Bern E; Division of Gastroenterology, Hepatology, and Nutrition, Boston, Massachusetts, USA., Sabharwal S; Division of Gastroenterology, Hepatology, and Nutrition, Boston, Massachusetts, USA., Leonard J; Division of Gastroenterology, Hepatology, and Nutrition, Boston, Massachusetts, USA., Richmond T; Division of Adolescent/Young Adult Medicine, Boston, Massachusetts, USA., Sawicki GS; Division of Pulmonary Medicine, Boston, Massachusetts, USA.
Jazyk: angličtina
Zdroj: Pediatric pulmonology [Pediatr Pulmonol] 2022 Nov; Vol. 57 (11), pp. 2791-2797. Date of Electronic Publication: 2022 Aug 17.
DOI: 10.1002/ppul.26102
Abstrakt: Introduction: There is evidence for increased risk of eating disorders in individuals with diet-treated chronic illnesses, however, data in patients with cystic fibrosis (CF) is less clear. No studies have evaluated avoidant/restrictive food intake disorder (ARFID) in the CF population. We investigated the prevalence of eating disorders, including ARFID, in adolescents and young adults with CF.
Methods: Patients with CF aged 14-35 years were recruited to complete three validated surveys: (1) Eating Disorder Examination Questionnaire (EDE-Q), (2) Nine-Item Avoidant/Restrictive Food Intake Disorder Scale (NIAS), and (3) Cystic Fibrosis Questionnaire-Revised (CFQ-R). Univariate linear regression analysis identified baseline risk factors associated with these survey scores. Variables with univariate p < 0.20 were considered for inclusion in a multivariable linear regression model. Backwards stepwise linear regression was used to identify the final model.
Results: A total of 52 patients enrolled. The prevalence of a positive screen on the EDE-Q was 9.6%, and on the NIAS was 13.5%. The CFQ-R eating and weight subscales were associated with scores on the EDE-Q, and CFQ-R eating subscale and being dF508 homozygous were correlated with the NIAS total score.
Discussion: A clinically significant number of participants screened positive for eating disorders on the EDE-Q and NIAS. Scores on the eating and weight scales of the CFQ-R were associated with the scores on these surveys. Further work is needed to better understand the optimal way to use such tools to screen and treat for eating disorders in individuals with CF.
(© 2022 Wiley Periodicals LLC.)
Databáze: MEDLINE
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