Total Arch Thoracic Endovascular Aortic Repair Using Double Fenestrated Physician-Modified Stent-Grafts: 100 Patients.

Autor:	Canaud L; Service de Chirurgie Vasculaire et Thoracique, Hôpital Arnaud de Villeneuve, Montpellier, France., Chassin-Trubert L; Service de Chirurgie Vasculaire et Thoracique, Hôpital Arnaud de Villeneuve, Montpellier, France.; Servicio de Cirugía Vascular y Endovascular, Clínica Universidad de los Andes, Las Condes, Chile., Abouliatim I; Department Vascular Surgery, Clinique Pasteur, Toulouse, France., Hireche K; Service de Chirurgie Vasculaire et Thoracique, Hôpital Arnaud de Villeneuve, Montpellier, France., Bacri C; Service de Chirurgie Vasculaire et Thoracique, Hôpital Arnaud de Villeneuve, Montpellier, France., Alric P; Service de Chirurgie Vasculaire et Thoracique, Hôpital Arnaud de Villeneuve, Montpellier, France., Gandet T; Service de Chirurgie Vasculaire et Thoracique, Hôpital Arnaud de Villeneuve, Montpellier, France.
Jazyk:	angličtina
Zdroj:	Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists [J Endovasc Ther] 2024 Feb; Vol. 31 (1), pp. 89-97. Date of Electronic Publication: 2022 Aug 04.
DOI:	10.1177/15266028221116747
Abstrakt:	Objective: The aim was to evaluate early and medium-term outcomes of double fenestrated physician-modified endovascular grafts for total endovascular aortic arch repair. Methods: This single-center retrospective analysis of prospectively-collected data included 100 patients, from January 2017 to December 2021, undergoing thoracic endovascular aortic repair (TEVAR) for zone 0. The fenestrations were a proximal larger fenestration that incorporated the brach2iocephalic trunk and left common carotid artery and a distal smaller fenestration for the left subclavian artery (LSA). Only the LSA fenestration was stented. Results: The median duration for stent-graft modification was 23±6 minutes. Of the 100 patients, 70 were men. The mean patient age was 70±10.5 years. Indications for treatment included degenerative aortic arch aneurysm (n=32), dissecting aortic arch aneurysm after type A dissections (n=23) and (n=19) after type B dissections, acute complicated type B dissection (n=16), and other pathologies (n=10). Technical success rate was 97%. The 30 day mortality was 2% (n=2). Four patients (4%) had minor stroke with full recovery. One patient (1%) had a type IA endoleak, 1 patient (1%) had a type IB endoleak, and 2 patients (2%) have a type II endoleak from the LSA. Eight patients (8%) required reintervention: 1 type IA endoleak, 1 type IB endoleak, 1 retrograde type A dissection, and 5 because of access-related complications. During a mean follow-up of 24±7.2 months, there were no aortic rupture, paraplegia, and all supra-aortic trunks were patent. Conclusions: Double homemade fenestrated TEVAR is both feasible and effective for total endovascular aortic arch repair avoiding the need for anatomical and extra-anatomical surgical revascularization. The long-term durability will need to be assessed in studies with long-term follow-up. Clinical Impact: Double homemade fenestrated TEVAR is effective for total endovascular aortic arch repair avoiding the need for anatomical and extra-anatomical surgical revascularization. The standout feature of this double fenestrated device is its simple handling during operation with the proximal fenestrations being directed to the orifices of the BT and LCCA automatically when the LSA fenestration is catheterized and secured by covered stent placement. The deployment algorithm actively steers the operator away from superfluous manipulations of the device within the arch and avoids guidewire manipulation in carotid arteries. The long-term durability will need to be assessed in studies with long-term follow-up. Competing Interests: Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Databáze:	MEDLINE
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