| Autor: |
Vinnik YS; Voino-Yasenetsky Krasnoyarsk State Medical University, Krasnoyarsk, Russia., Teplyakova OV; Voino-Yasenetsky Krasnoyarsk State Medical University, Krasnoyarsk, Russia., Erguleeva AD; Voino-Yasenetsky Krasnoyarsk State Medical University, Krasnoyarsk, Russia. |
| Jazyk: |
ruština |
| Zdroj: |
Khirurgiia [Khirurgiia (Mosk)] 2022 (8), pp. 90-97. |
| DOI: |
10.17116/hirurgia202208190 |
| Abstrakt: |
Modern literature data confirm the central role of intestinal barrier complex not only as a target in acute necrotizing pancreatitis, but also as a trigger for septic complications. Intra-abdominal hypertension, endothelial dysfunction and gut microbiome changes following necrotizing pancreatitis might have an independent impact on acute intestinal distress syndrome and bacterial translocation. Monitoring of these conditions and early target therapy can improve the outcomes in patients with severe acute pancreatitis. Adverse outcomes of infected pancreatic necrosis including high mortality and morbidity are largely due to the prevalence of multidrug-resistant bacterial pathogens. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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