Co-existence of mixed meibomian gland and ductal adenoma with an apocrine sweat gland cyst in a dog: histological and immunohistochemical analyses.
| Autor: | Alidadi S; Department of Pathobiology, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran., Nourani H; Department of Pathobiology, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran., Vakili T; Private Veterinary Practitioner, Aftab Pets Specialty Clinic, Mashhad, Iran., Hassanabadi M; Department of Clinical Sciences, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran. |
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| Jazyk: | angličtina |
| Zdroj: | Veterinary research forum : an international quarterly journal [Vet Res Forum] 2022 Jun; Vol. 13 (2), pp. 289-292. Date of Electronic Publication: 2022 Jun 15. |
| DOI: | 10.30466/vrf.2021.534469.3216 |
| Abstrakt: | A 14-year- old female Shih Tzu was presented with conjunctivitis, keratitis, an enlarged mass located on the left lower eyelid and a large subcutaneous cyst in the temporal region. The hematological and biochemical analyses revealed no significant issues. The mass and the cyst were taken from the base with 1.50 cm of the underlying tissue. On histological examination, the mass was made up of adenoid arrangements of sebocytes and basaloid reserve cells with low to moderate mitotic activity of basaloid cells. In addition, a large number of meibomian ducts with marked infiltration of mononuclear inflammatory cells and melanin pigment were observed in the ductal part of the tumor. The cyst was lined by a simple cuboid-like epithelium with no eosinophilic cuticular lining. Immuno-histochemical staining of the mass with CK14 showed positive reaction in the neoplastic basaloid reserve cells and adipocytes; but, not with CK18 and vimentin. Unlike, the luminal cells of the cyst were stained with CK18. The co-existence of mixed meibomian gland and ductal adenoma with an apocrine sweat gland cyst was diagnosed based on the clinical, histological and immunohistochemical findings. Competing Interests: The authors declare no potential conflicts of interest with respect to the research, authorship, and/or publication of this article. (© 2022 Urmia University. All rights reserved.) |
| Databáze: | MEDLINE |
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