Effect of one and two sessions of antimicrobial photodynamic therapy on clinical and microbial outcomes of non-surgical management of chronic periodontitis: A clinical study.

Autor: Lafzi A; Department of Periodontics, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran., Mojahedi SM; Department of Laser, Dental School, Shahid Beheshti University of Medical Sciences, Tehran, Iran., Mirakhori M; Dental Research Center, Research Institute of Dental Sciences, school of dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran., Torshabi M; Dental Biomaterials Department, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran., Kadkhodazadeh M; Department of Periodontics, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran., Amid R; Department of Periodontics, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran., Karamshahi M; Department of Periodontics, School of Dentistry, Qazvin University of Medical Sciences, Qazvin, Iran., Arbabi M; DDS, Private Practice, Tehran, Iran., Torabi H; DDS, Private Practice, Tehran, Iran.
Jazyk: angličtina
Zdroj: Journal of advanced periodontology & implant dentistry [J Adv Periodontol Implant Dent] 2019 Dec 18; Vol. 11 (2), pp. 85-93. Date of Electronic Publication: 2019 Dec 18 (Print Publication: 2019).
DOI: 10.15171/japid.2019.014
Abstrakt: Background: This study aimed to compare the effect of one and two sessions of antimicrobial photodynamic therapy (aPDT) as an adjunct to scaling and root planing (SRP) on clinical and microbial parameters in patients with chronic periodontitis.
Methods: This study was conducted on 20 patients. The dental quadrants of patients were randomly assigned to SRP at baseline (group 1), SRP at baseline and one month (group 2), SRP plus aPDT at baseline (group 3) and SRP plus aPDT at baseline and one month (group 4). Probing depth (PD), clinical attachment level (CAL) gain, and bleeding on probing (BoP) were measured at baseline, and one and three months later. F. nucleatum counts were determined by PCR. ANOVA was used for the comparison of these variables between the groups.
Results: In all the groups, PD reduction and CAL gain increased significantly at 1- and 3-month intervals compared to baseline (P=0.001). At three months, the difference in PD between groups 1 and 3 was statistically significant (P=0.014). CAL gain between groups 2 and 4 at one month (P=0.016) and three months (P=0.001) wasstatistically significant. Reduction in F. nucleatum counts was not significant between the four study groups (P>0.05).
Conclusion: A combination of two sessions of aPDT and SRP could improve CAL gain; however, further long-term studies are necessary in this regard.
Competing Interests: The authors declare no conflict(s) of interest related to the publication of this work.
(© 2019 The Author(s).)
Databáze: MEDLINE