Glossitis in an older non-corgi dog: Diagnosis and long-term follow-up.

Autor:	Krenzke LR; University of Wisconsin - Madison, School of Veterinary Medicine, Department of Medical Sciences, Madison, Wisconsin, USA (Krenzke, Cameron, Pritchard); Southeast Veterinary Neurology of Boynton Beach, Boynton Beach, Florida, USA (Webb); Comparative Neuromuscular Laboratory, University of California - San Diego, La Jolla, California, USA (Guo, Shelton)., Cameron S; University of Wisconsin - Madison, School of Veterinary Medicine, Department of Medical Sciences, Madison, Wisconsin, USA (Krenzke, Cameron, Pritchard); Southeast Veterinary Neurology of Boynton Beach, Boynton Beach, Florida, USA (Webb); Comparative Neuromuscular Laboratory, University of California - San Diego, La Jolla, California, USA (Guo, Shelton)., Pritchard JC; University of Wisconsin - Madison, School of Veterinary Medicine, Department of Medical Sciences, Madison, Wisconsin, USA (Krenzke, Cameron, Pritchard); Southeast Veterinary Neurology of Boynton Beach, Boynton Beach, Florida, USA (Webb); Comparative Neuromuscular Laboratory, University of California - San Diego, La Jolla, California, USA (Guo, Shelton)., Webb DB; University of Wisconsin - Madison, School of Veterinary Medicine, Department of Medical Sciences, Madison, Wisconsin, USA (Krenzke, Cameron, Pritchard); Southeast Veterinary Neurology of Boynton Beach, Boynton Beach, Florida, USA (Webb); Comparative Neuromuscular Laboratory, University of California - San Diego, La Jolla, California, USA (Guo, Shelton)., Guo LT; University of Wisconsin - Madison, School of Veterinary Medicine, Department of Medical Sciences, Madison, Wisconsin, USA (Krenzke, Cameron, Pritchard); Southeast Veterinary Neurology of Boynton Beach, Boynton Beach, Florida, USA (Webb); Comparative Neuromuscular Laboratory, University of California - San Diego, La Jolla, California, USA (Guo, Shelton)., Shelton GD; University of Wisconsin - Madison, School of Veterinary Medicine, Department of Medical Sciences, Madison, Wisconsin, USA (Krenzke, Cameron, Pritchard); Southeast Veterinary Neurology of Boynton Beach, Boynton Beach, Florida, USA (Webb); Comparative Neuromuscular Laboratory, University of California - San Diego, La Jolla, California, USA (Guo, Shelton).
Jazyk:	angličtina
Zdroj:	The Canadian veterinary journal = La revue veterinaire canadienne [Can Vet J] 2022 Aug; Vol. 63 (8), pp. 825-829.
Abstrakt:	A 9-year-old spayed female 18.8 kg mixed breed boxer dog was referred for evaluation of a 7-month history of difficulty swallowing and prehending food, regurgitation, hypersalivation, and an abnormal dorsiflexion of the tongue. Prior to referral, a barium study was performed, which revealed a mildly dilated esophagus. Treatment with sucralfate, cisapride, and prednisone was initiated. Physical examination revealed bilateral, symmetric atrophy of the temporalis muscles, dorsiflexion of the distal aspect of the tongue with concurrent muscle atrophy, and a reduced gag reflex. Electrodiagnostic examinations revealed spontaneous electrical activity in the muscles of mastication and tongue. Biopsies from the right temporalis, tongue, and biceps femoris muscles were collected. An immune-mediated myositis with fibrosis, scattered CD3, CD4, and CD8+ T-lymphocytes, and upregulation of markers for major histocompatibility antigens were observed in the tongue and temporalis muscles. The dog was treated with a tapering course of prednisone over 2 months and cyclosporine long-term. The dog was maintained on cyclosporine alone for > 2 years and clinical signs remained static, although multiple episodes of aspiration pneumonia occurred. Ultimately, euthanasia was performed due to chronic kidney disease with associated anemia, lethargy, and anorexia. (Copyright and/or publishing rights held by the Canadian Veterinary Medical Association.)
Databáze:	MEDLINE
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