Periodontitis and implant complications in diabetes.

Autor: Nibali L; Periodontology Unit, Centre for Host Microbiome Interactions, Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, London, UK., Gkranias N; Centre for Immunobiology and Regenerative Medicine and Centre for Oral Clinical Research, Institute of Dentistry, Queen Mary University London (QMUL), London, UK., Mainas G; Periodontology Unit, Centre for Host Microbiome Interactions, Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, London, UK., Di Pino A; Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy.
Jazyk: angličtina
Zdroj: Periodontology 2000 [Periodontol 2000] 2022 Oct; Vol. 90 (1), pp. 88-105. Date of Electronic Publication: 2022 Aug 01.
DOI: 10.1111/prd.12451
Abstrakt: Epidemiologic evidence indicates that periodontitis is more frequent in patients with uncontrolled diabetes mellitus than in healthy controls, suggesting that it could be considered the "sixth complication" of diabetes. Actually, diabetes mellitus and periodontitis are two extraordinarily prevalent chronic diseases that share a number of comorbidities all converging toward an increased risk of cardiovascular disease. Periodontal treatment has recently been shown to have the potential to improve the metabolic control of diabetes, although long-term studies are lacking. Uncontrolled diabetes also seems to affect the response to periodontal treatment, as well as the risk to develop peri-implant diseases. Mechanisms of associations between diabetes mellitus and periodontal disease include the release of advanced glycation end products as a result of hyperglycemia and a range of shared predisposing factors of genetic, microbial, and lifestyle nature. This review discusses the evidence for the risk of periodontal and peri-implant disease in diabetic patients and the potential role of the dental professional in the diabetes-periodontal interface.
(© 2022 The Authors. Periodontology 2000 published by John Wiley & Sons Ltd.)
Databáze: MEDLINE
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