A Case of Macrophage Activation Syndrome Manifesting as the Initial Presentation of Systemic Lupus Erythematosus.
| Autor: | Suwal A; Internal medicine, Reading Hospital-Tower Health, Reading, USA., Shrestha B; Internal Medicine, Reading Hospital-Tower Health, Reading, USA., Paudel A; Internal Medicine, Reading Hospital-Tower Health, Reading, USA., Paudel R; Internal Medicine, Reading Hospital-Tower Health, Reading, USA., Basnet S; Internal Medicine, Reading Hospital-Tower Health, Reading, USA. |
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| Jazyk: | angličtina |
| Zdroj: | Cureus [Cureus] 2022 Jun 27; Vol. 14 (6), pp. e26375. Date of Electronic Publication: 2022 Jun 27 (Print Publication: 2022). |
| DOI: | 10.7759/cureus.26375 |
| Abstrakt: | Macrophage activation syndrome (MAS) is a potentially fatal complication of an autoimmune rheumatologic disease characterized by overwhelming inflammation, multiorgan failure, and high mortality if untreated. We report a rare case of a 56-year-old man who presented with fever for three weeks and had a constellation of clinical features and laboratory findings, meeting the diagnostic criteria for systemic lupus erythematosus (SLE) and SLE-associated MAS. He was treated with high dose intravenous corticosteroid and hydroxychloroquine, resulting in resolution of fever and dramatic clinical improvement. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2022, Suwal et al.) |
| Databáze: | MEDLINE |
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