Whey protein improves glycemia during an oral glucose tolerance test compared to vigorous-intensity aerobic exercise in young adult men.

Autor: Gordon RA; Department of Biology, Drury University, Springfield, MO, USA. rgordon002@drury.edu., Zumbro EL; Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.; UAB Center for Exercise Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Castleberry TJ; Department of Kinesiology, Louisiana Tech University, Ruston, LA, USA., Sokoloski ML; School of Health Promotion and Kinesiology, Texas Woman's University, Denton, TX, USA., Brisebois MF; Department of Human Performance and Health, University of South Carolina Upstate, Spartanburg, SC, USA., Irvine CJ; Department of Health and Human Performance, Rocky Mountain College, Billings, MT, USA., Duplanty AA; School of Health Promotion and Kinesiology, Texas Woman's University, Denton, TX, USA., Ben-Ezra V; School of Health Promotion and Kinesiology, Texas Woman's University, Denton, TX, USA.
Jazyk: angličtina
Zdroj: BMC sports science, medicine & rehabilitation [BMC Sports Sci Med Rehabil] 2022 Jul 30; Vol. 14 (1), pp. 147. Date of Electronic Publication: 2022 Jul 30.
DOI: 10.1186/s13102-022-00540-z
Abstrakt: Background: Both aerobic exercise and whey protein can improve glucose regulation. The purpose of this study was to investigate how a single bout of vigorous-intensity aerobic exercise and whey protein, independently, as well as when combined, influence glycemia during an oral glucose tolerance test in sedentary, young men.
Methods: Healthy males (n = 11) completed four randomized trials: no exercise/no whey protein (R); exercise (EX; walking at 70% VO 2max for 60 min); 50 g of whey protein (W); and exercise combined with 50 g of whey protein (EXW). Each trial included a 75 g oral glucose tolerance test (OGTT) that was completed after an overnight fast. Blood samples were collected over a two-hour period during the OGTT. For EX and EXW, the exercise was performed the evening before the OGTT and the 50 g of whey protein was dissolved in 250 mL of water and was consumed as a preload 30 min prior to the OGTT. For R and EX, participants consumed 250 mL of water prior to the OGTT. Plasma samples were analyzed for glucose, insulin, C-peptide, glucagon, gastric inhibitory peptide (GIP) and glucagon like peptide 1 (GLP-1), and postprandial incremental area under the curve (iAUC) was calculated for each.
Results: Glucose iAUC was reduced during W (- 32.9 ± 22.3 mmol/L) compared to R (122.7 ± 29.8 mmol/L; p < 0.01) and EX (154.3 ± 29.2 mmol/L; p < 0.01). Similarly, glucose iAUC was reduced for EXW (17.4 ± 28.9 mmol/L) compared to R and EX (p < 0.01 for both). There were no differences in iAUC for insulin, C-peptide, GIP, GLP-1, and glucagon between the four trials. Insulin, C-peptide, glucagon, GIP, and GLP-1 were elevated during the whey protein preload period for W and EXW compared to EX and R (p < 0.01). There were no differences for insulin, C-peptide, glucagon, GIP, or GLP-1 between trials for the remaining duration of the OGTT.
Conclusions: Glucose responses during an oral glucose tolerance test were improved for W compared to EX. There were no additional improvements in glucose responses when vigorous-intensity aerobic exercise was combined with whey protein (EXW).
(© 2022. The Author(s).)
Databáze: MEDLINE
Externí odkaz: