An evaluation of M 2+ interference correction approaches associated with As and Se in ICP-MS using a multi-day dataset along with ICP-MS/MS/HR-ICP-MS based analysis and hierarchical modeling as a means of assessing bias in fortified drinking waters and single component matrices.

Autor:	Smith SW; University of Cincinnati, U.S. Environmental Protection Agency (USEPA) Research Trainee, Center for Environmental Solutions and Emergency Response (CESER), Cincinnati, OH 45268, USA.; U.S. Food and Drug Administration, Forensic Chemistry Center, Cincinnati, OH 45237, USA., Martin RW; USEPA, Center for Environmental Measurement and Modeling (CEMM), Cincinnati, OH 45268, USA., Hanks N; Student Service Contractor, USEPA, CESER, Cincinnati, OH 45268, USA., Creed PA; USEPA, CESER, 26 W. Martin Luther King Drive, Cincinnati, OH 45268, USA., Kovalcik K; USEPA, Center for Environmental Measurement and Modeling (CEMM), Research Triangle Park, NC 27711, USA., Wilson RA; U.S. Food and Drug Administration, Forensic Chemistry Center, Cincinnati, OH 45237, USA., Kubachka K; U.S. Food and Drug Administration, Forensic Chemistry Center, Cincinnati, OH 45237, USA., Brisbin JA; USEPA, Office of Ground Water and Drinking Water, Cincinnati, OH 45268, USA., Figueroa JAL; University of Cincinnati, Department of Chemistry, Cincinnati, OH 45221, USA., Creed JT; USEPA, CESER, 26 W. Martin Luther King Drive, Cincinnati, OH 45268, USA.
Jazyk:	angličtina
Zdroj:	Journal of analytical atomic spectrometry [J Anal At Spectrom] 2022 Mar 18; Vol. 37, pp. 898-909.
DOI:	10.1039/d1ja00407g
Abstrakt:	Three 1 2 mass oriented rare earth element (REE) M ²⁺ correction approaches (fixed factor, a dual internal standard, and an in-sample) are evaluated for use in an ICP-MS environmental method update. The multi-variant-based evaluation includes analyzing the same 19 REE-fortified matrices on eight different days over a two-month period using two instrument tunes. These REE-fortified matrices were also analyzed using HR-ICP-MS and ICP-MS/MS to estimate the reference value for use in the principal component analysis (PCA) and hierarchical modeling evaluation. A fixed factor is unable to compensate for matrix and mass dependent drift and because of this it generates the largest across matrix, tune, and day 95 ^th percent confidence bounds for the REE corrections on both As (1.1 ppb) and Se (23 ppb) using samples fortified with 100 ppb Nd, Sm & Gd. The PCA analysis indicated that M ²⁺ ions cluster together across matrix, tune and day better than M ¹⁺ and these tighter correlations are reflected in reduced 95 ^th percentile confidence bounds for dual M ²⁺ internal standards (M ²⁺ ; As = 0.3 ppb; Se = 5.4 ppb; n = 704) relative to M ¹⁺ internal standards (M ¹⁺ ; As = 0.6 ppb; Se = 12.0 ppb; n = 1056). The use of an in-sample M ²⁺ correction produced comparable 95 ^th percent confidence bounds (As = 0.2 ppb; Se = 3.4 ppb; n = 352) relative to the M ²⁺ internal standard approaches. Finally, the hierarchical modeling indicated M ²⁺ ions as internal standards tend to minimize the across day variability induced by cone changes and the daily reoccurring matrix shifts in the M ²⁺ /M ¹⁺ ratio associated with 250 ppm matrices of Na, Ca, and Mg. This internal standard driven reduction in variability can be beneficial in compliance monitoring methods. Competing Interests: Conflicts of interest There are no conflicts to declare.
Databáze:	MEDLINE
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