Postpartum Relapse in Patients with Bipolar Disorder.

Autor: Conejo-Galindo J; Psychiatry Department, Institute of Psychiatry and Mental Health, Hospital General Universitario Gregorio Marañón, 28007 Madrid, Spain.; Alcalamente, Mental Health Service, 28806 Alcalá de Henares, Spain., Sanz-Giancola A; Psychiatry Department, Principe de Asturias University Hospital, 28805 Alcalá de Henares, Spain., Álvarez-Mon MÁ; Department of Medicine and Medical Specialities, Faculty of Medicine and Health Sciences, University of Alcalá, 28801 Alcalá de Henares, Spain.; Department of Psychiatry and Mental Health, Hospital Universitario Infanta Leonor, 28031 Madrid, Spain.; Ramón y Cajal Institute of Sanitary Research (IRYCIS), 28034 Madrid, Spain., Ortega MÁ; Department of Medicine and Medical Specialities, Faculty of Medicine and Health Sciences, University of Alcalá, 28801 Alcalá de Henares, Spain.; Ramón y Cajal Institute of Sanitary Research (IRYCIS), 28034 Madrid, Spain., Gutiérrez-Rojas L; Department of Psychiatry, Faculty of Medicine, University of Granada, 18016 Granada, Spain., Lahera G; Psychiatry Department, Principe de Asturias University Hospital, 28805 Alcalá de Henares, Spain.; Department of Medicine and Medical Specialities, Faculty of Medicine and Health Sciences, University of Alcalá, 28801 Alcalá de Henares, Spain.; Ramón y Cajal Institute of Sanitary Research (IRYCIS), 28034 Madrid, Spain.; Biomedical Research Networking Centre in Mental Health (CIBERSAM), 28029 Madrid, Spain.
Jazyk: angličtina
Zdroj: Journal of clinical medicine [J Clin Med] 2022 Jul 08; Vol. 11 (14). Date of Electronic Publication: 2022 Jul 08.
DOI: 10.3390/jcm11143979
Abstrakt: Pregnancy and postpartum are vital times of greater vulnerability to suffer a decompensation of bipolar disorder (BD).
Methods: A systematic literature search was performed on public electronic medical databases, following PRISMA guidelines. Studies were included if they reported postpartum relapse in patients diagnosed with BD according to Diagnosis Statistical Manual (DSM) or International Classification Disease (ICD) criteria.
Results: Sixteen articles describing 6064 deliveries of 3977 women were included in the quantitative analyses. The overall risk of postpartum relapse was 36.77%. The methodology of the studies, the diagnostic criteria, the discrimination between BD type I and II, and the origin of the sample were very heterogeneous.
Conclusions: the rate of postpartum bipolar relapse is very high, as it is considered to be a critical period. It is especially important to detect decompensation in this period and to evaluate mood-stabilizing treatment, given the high risk of relapse concentrated in a short period.
Databáze: MEDLINE
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