Uterine Artery Embolization of Uterine Arteriovenous Malformation: A Systematic Review of Success Rate, Complications, and Posterior Pregnancy Outcomes.

Autor:	Ruiz Labarta FJ; Department of Public and Maternal and Child Health, School of Medicine, Complutense University of Madrid, 28040 Madrid, Spain.; Maternal Fetal Medicine Research Group, School of Medicine, Complutense University of Madrid, 28040 Madrid, Spain.; Group of Pathophysiology in Women, Pregnancy, Labor, and Puerperium, Health Research Institute Gregorio Marañón, 28040 Madrid, Spain.; Maternal and Infant Research Investigation Unit, Alonso Family Foundation (UDIMIFFA), 28009 Madrid, Spain., Pintado Recarte MP; Department of Public and Maternal and Child Health, School of Medicine, Complutense University of Madrid, 28040 Madrid, Spain.; Maternal Fetal Medicine Research Group, School of Medicine, Complutense University of Madrid, 28040 Madrid, Spain.; Group of Pathophysiology in Women, Pregnancy, Labor, and Puerperium, Health Research Institute Gregorio Marañón, 28040 Madrid, Spain.; Maternal and Infant Research Investigation Unit, Alonso Family Foundation (UDIMIFFA), 28009 Madrid, Spain., González Leyte M; Group of Pathophysiology in Women, Pregnancy, Labor, and Puerperium, Health Research Institute Gregorio Marañón, 28040 Madrid, Spain.; Department of Radiology, Division of Interventional Radiology, Hospital General Universitario Gregorio Marañón, Universidad Complutense de Madrid, 28040 Madrid, Spain., Arribas CB; Department of Public and Maternal and Child Health, School of Medicine, Complutense University of Madrid, 28040 Madrid, Spain.; Maternal Fetal Medicine Research Group, School of Medicine, Complutense University of Madrid, 28040 Madrid, Spain.; Group of Pathophysiology in Women, Pregnancy, Labor, and Puerperium, Health Research Institute Gregorio Marañón, 28040 Madrid, Spain.; Maternal and Infant Research Investigation Unit, Alonso Family Foundation (UDIMIFFA), 28009 Madrid, Spain., Álvarez Luque A; Group of Pathophysiology in Women, Pregnancy, Labor, and Puerperium, Health Research Institute Gregorio Marañón, 28040 Madrid, Spain.; Department of Radiology, Division of Interventional Radiology, Hospital General Universitario Gregorio Marañón, Universidad Complutense de Madrid, 28040 Madrid, Spain., Cuñarro López Y; Department of Public and Maternal and Child Health, School of Medicine, Complutense University of Madrid, 28040 Madrid, Spain.; Maternal Fetal Medicine Research Group, School of Medicine, Complutense University of Madrid, 28040 Madrid, Spain.; Group of Pathophysiology in Women, Pregnancy, Labor, and Puerperium, Health Research Institute Gregorio Marañón, 28040 Madrid, Spain.; Maternal and Infant Research Investigation Unit, Alonso Family Foundation (UDIMIFFA), 28009 Madrid, Spain., García-Montero C; Department of Medicine and Medical Specialities, Faculty of Medicine and Health Sciences, University of Alcalá, 28801 Alcala de Henares, Spain.; Ramón y Cajal Institute of Sanitary Research (IRYCIS), 28034 Madrid, Spain., Fraile-Martinez O; Department of Medicine and Medical Specialities, Faculty of Medicine and Health Sciences, University of Alcalá, 28801 Alcala de Henares, Spain.; Ramón y Cajal Institute of Sanitary Research (IRYCIS), 28034 Madrid, Spain., Ortega MA; Department of Medicine and Medical Specialities, Faculty of Medicine and Health Sciences, University of Alcalá, 28801 Alcala de Henares, Spain.; Ramón y Cajal Institute of Sanitary Research (IRYCIS), 28034 Madrid, Spain., De León-Luis JA; Department of Public and Maternal and Child Health, School of Medicine, Complutense University of Madrid, 28040 Madrid, Spain.; Maternal Fetal Medicine Research Group, School of Medicine, Complutense University of Madrid, 28040 Madrid, Spain.; Group of Pathophysiology in Women, Pregnancy, Labor, and Puerperium, Health Research Institute Gregorio Marañón, 28040 Madrid, Spain.; Maternal and Infant Research Investigation Unit, Alonso Family Foundation (UDIMIFFA), 28009 Madrid, Spain.
Jazyk:	angličtina
Zdroj:	Journal of personalized medicine [J Pers Med] 2022 Jul 01; Vol. 12 (7). Date of Electronic Publication: 2022 Jul 01.
DOI:	10.3390/jpm12071098
Abstrakt:	Uterine Arteriovenous Malformation (UAVM) is a rare but life-threating cause of uterine bleeding. The clinical management of this condition is challenging, and there is a need to describe the most adequate approach for these patients. Uterine artery embolization (UAE) is the most widely-published treatment in the literature in recent years, although there is a need to update the evidence on this treatment and to compare it with other available therapies. Thus, the objective of this systematic review is to quantify the efficacy of UAE of UAVM. In addition, we evaluated the clinical context of the patients included, the treatment complications, and the pregnancy outcomes after UAE. With this goal in mind, we finally included 371 patients spread over all continents who were included in 95 studies. Our results show that, similar to other medical therapies, the global success rate after embolization treatment was 88.4%, presenting a low risk of adverse outcomes (1.8%), even in women with later pregnancy (77% had no complications). To date, this is the largest systematic review conducted in this field, although there are still some points to address in future studies. The results obtained in our study should be outlined in UAE protocols and guidelines to aid in clinical decision-making in patients with UAVM.
Databáze:	MEDLINE
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