Air Pollution and Its Devastating Effects on the Central Nervous System.

Autor: Sîrbu CA; Department of Neurology, 'Dr. Carol Davila' Central Military Emergency University Hospital, 010242 Bucharest, Romania., Stefan I; Department of Infectious Diseases, 'Dr. Carol Davila' Central Military Emergency University Hospital, 010242 Bucharest, Romania.; Department of Medico-Surgical and Prophylactic Disciplines, Titu Maiorescu University, 031593 Bucharest, Romania., Dumitru R; Department of Neurology, 'Dr. Carol Davila' Central Military Emergency University Hospital, 010242 Bucharest, Romania., Mitrica M; Clinical Neurosciences Department, University of Medicine and Pharmacy 'Carol Davila' Bucharest, 050474 Bucharest, Romania., Manole AM; Department of Neurology, Clinical Ambulatory, 'Dr. Carol Davila' Central Military Emergency University Hospital, 010242 Bucharest, Romania., Vasile TM; Clinical Neurosciences Department, University of Medicine and Pharmacy 'Carol Davila' Bucharest, 050474 Bucharest, Romania., Stefani C; Department of Family Medicine and Clinical Base, 'Dr. Carol Davila' Central Military Emergency University Hospital, 010242 Bucharest, Romania.; Department No. 5, University of Medicine and Pharmacy 'Carol Davila', 050474 Bucharest, Romania., Ranetti AE; Department No. 2, University of Medicine and Pharmacy 'Carol Davila', 050474 Bucharest, Romania.
Jazyk: angličtina
Zdroj: Healthcare (Basel, Switzerland) [Healthcare (Basel)] 2022 Jun 23; Vol. 10 (7). Date of Electronic Publication: 2022 Jun 23.
DOI: 10.3390/healthcare10071170
Abstrakt: Air pollution is a real public health problem, it being one of the five most common causes of mortality in developing countries. However, pollution studies have focused on the cardiovascular and pulmonary systems in recent decades. Recently, researchers have moved towards a new direction, tracing a direct link between pollution and stroke. Stroke has many known risk factors such as smoking, a sedentary lifestyle, and hypertension. Pollution is universally widespread, already a matter of public interest, so that, although intuitive, it is difficult to connect the two. The particles found in the air that we breathe, regardless of their origin, can attack the body in different ways, causing inflammation, and triggering a true cascade of phenomena that end up attacking the central nervous system and other organs. This article tries to explain the series of phenomena that determine the harmful effect of particles present in the air, with an increased focus on the central nervous system and especially on strokes. A deeper understanding of these phenomena helps in guiding future studies and finding viable solutions to protect people at risk.
Databáze: MEDLINE