[IgG4-related disease of the breast].

Autor: Rybakova MG; Pavlov First Saint Petersburg State Medical University, Saint Petersburg, Russia., Mylnikova AA; Pavlov First Saint Petersburg State Medical University, Saint Petersburg, Russia., Vlasova MT; Pavlov First Saint Petersburg State Medical University, Saint Petersburg, Russia.
Jazyk: ruština
Zdroj: Arkhiv patologii [Arkh Patol] 2022; Vol. 84 (4), pp. 51-55.
DOI: 10.17116/patol20228404151
Abstrakt: IgG4-related disease is an immune-mediated disorder with tumor-like multiorgan involvement, elevated serum IgG4 level and specific histopathological appearance (lymphoplasmacytic infiltrate rich in IgG4+ plasma cells and storiform fibrosis). The article presents rare clinical and morphological observations of IgG4-related mastopathy in women with suspected tumor process. A strategy for the treatment of IgG4-related disease should be based on the results of pre-surgery histopathological examination, which may help to avoid unreasonable surgical intervention and choose glucocorticoids or rituximab as the first-line treatment.
Databáze: MEDLINE