Investigating the Dialysis Treatment Using Hollow Fiber Membrane: A New Approach by CFD.

Autor: Magalhães HLF; Department of Chemical Engineering, Federal University of Campina Grande, Campina Grande 58429-900, Brazil., Gomez RS; Department of Mechanical Engineering, Federal University of Campina Grande, Campina Grande 58429-900, Brazil., Leite BE; Department of Process Engineering, Federal University of Campina Grande, Campina Grande 58429-900, Brazil., Nascimento JBS; Department of Process Engineering, Federal University of Campina Grande, Campina Grande 58429-900, Brazil.; Department of Exact Sciences and Technology, Santa Cruz State University, Ilhéus 46662-900, Brazil., Brito MKT; Department of Process Engineering, Federal University of Campina Grande, Campina Grande 58429-900, Brazil., Araújo MV; Department of Process Engineering, Federal University of Campina Grande, Campina Grande 58429-900, Brazil., Cavalcante DCM; Federal Institute of Education, Science and Technology of Sertão Pernambucano, Serra Talhada 56915-899, Brazil., Lima ES; Department of Process Engineering, Federal University of Campina Grande, Campina Grande 58429-900, Brazil., Lima AGB; Department of Mechanical Engineering, Federal University of Campina Grande, Campina Grande 58429-900, Brazil.; Department of Process Engineering, Federal University of Campina Grande, Campina Grande 58429-900, Brazil., Farias Neto SR; Department of Chemical Engineering, Federal University of Campina Grande, Campina Grande 58429-900, Brazil.; Department of Process Engineering, Federal University of Campina Grande, Campina Grande 58429-900, Brazil.
Jazyk: angličtina
Zdroj: Membranes [Membranes (Basel)] 2022 Jul 15; Vol. 12 (7). Date of Electronic Publication: 2022 Jul 15.
DOI: 10.3390/membranes12070710
Abstrakt: Due to the increase in the number of people affected by chronic renal failure, the demand for hemodialysis treatment has increased considerably over the years. In this sense, theoretical and experimental studies to improve the equipment (hemodialyzer) are extremely important, due to their potential impact on the patient's life quality undergoing treatment. To contribute to this research line, this work aims to study the fluid behavior inside a hollow fiber dialyzer using computational fluid dynamics. In that new approach, the blood is considered as multiphase fluid and the membrane as an extra flow resistance in the porous region (momentum sink). The numerical study of the hemodialysis process was based on the development of a mathematical model that allowed analyzing the performance of the system using Ansys ® Fluent software. The predicted results were compared with results reported in the literature and a good concordance was obtained. The simulation results showed that the proposed model can predict the fluid behavior inside the hollow fiber membrane adequately. In addition, it was found that the clearance decreases with increasing radial viscous resistance, with greater permeations in the vicinity of the lumen inlet region, as well as the emergence of the retrofiltration phenomenon, characteristic of this type of process. Herein, velocity, pressure, and volumetric fraction fields are presented and analyzed.
Databáze: MEDLINE
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