Photoinactivation of Aedes aegypti larvae using riboflavin as photosensitizer.

Autor: Lima AR; Grupo de Óptica e Fotônica, Instituto de Física, Universidade Federal de Mato Grosso do Sul, CP 549, Campo Grande, MS 79070-900, Brazil; São Carlos Institute of Physics, University of São Paulo, São Carlos 13566-590, Brazil. Electronic address: ramosalessandra09@gmail.com., da Silva CM; Grupo de Óptica e Fotônica, Instituto de Física, Universidade Federal de Mato Grosso do Sul, CP 549, Campo Grande, MS 79070-900, Brazil., Caires CSA; Grupo de Espectroscopia e Bioinformática Aplicados a Biodiversidade e a Saúde, Faculdade de Medicina, CP 549, Campo Grande, MS 79070-900, Brazil., Chaves H; Grupo de Óptica e Fotônica, Instituto de Física, Universidade Federal de Mato Grosso do Sul, CP 549, Campo Grande, MS 79070-900, Brazil., Pancrácio AS; Grupo de Óptica e Fotônica, Instituto de Física, Universidade Federal de Mato Grosso do Sul, CP 549, Campo Grande, MS 79070-900, Brazil., de Arruda EJ; Faculdade de Ciências Exatas e Tecnologia, Universidade Federal da Grande Dourados, CP 533, Dourados, MS 79804-970, Brazil., Caires ARL; Grupo de Óptica e Fotônica, Instituto de Física, Universidade Federal de Mato Grosso do Sul, CP 549, Campo Grande, MS 79070-900, Brazil., Oliveira SL; Grupo de Óptica e Fotônica, Instituto de Física, Universidade Federal de Mato Grosso do Sul, CP 549, Campo Grande, MS 79070-900, Brazil. Electronic address: samuel.oliveira@ufms.br.
Jazyk: angličtina
Zdroj: Photodiagnosis and photodynamic therapy [Photodiagnosis Photodyn Ther] 2022 Sep; Vol. 39, pp. 103030. Date of Electronic Publication: 2022 Jul 21.
DOI: 10.1016/j.pdpdt.2022.103030
Abstrakt: More than half of the global population lives in areas where the Aedes aegypti mosquito is present. Efforts have been made to deal with the population of this mosquito in the larval and adult stages to prevent outbreaks of diseases (Dengue, Zika, Chikungunya, and Yellow Fever). In this scenario, photodynamic inactivation may be an effective alternative method to control this vector population. To evaluate the efficacy of the riboflavin - B2 vitamin - as photosensitizer (PS) in the photodynamic inactivation of Ae. aegypti larvae, different concentrations (0; 0.005; 0.010; 0.025; 0.050; 0.075 and 0.100 mg mL -1 ) were evaluated under white light from RGB LEDs at a light dose of 495.2  J cm -2 . The results reveal that riboflavin can be successfully applied as a PS agent to photoinactivate Ae. aegypti larvae, showing its potential to deal with the larvae population.
Competing Interests: Declaration of Competing Interest The authors declare no conflicts of interest.
(Copyright © 2022 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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