Management of Symptomatic Vascularized Retained Products of Conception by Proximal Uterine Artery Embolization with Gelatin Sponge Torpedoes.

Autor:	Mathieu E; University of Grenoble Alpes, Grenoble, France; Department of Radiology, Grenoble Alpes University Hospital, Grenoble, France., Riethmuller D; University of Grenoble Alpes, Grenoble, France; Department of Obstetrics and Gynecology, Grenoble Alpes University Hospital, Grenoble, France., Delouche A; Department of Radiology, Grenoble Alpes University Hospital, Grenoble, France., Sicot M; Department of Obstetrics and Gynecology, Grenoble Alpes University Hospital, Grenoble, France., Teyssier Y; Department of Radiology, Grenoble Alpes University Hospital, Grenoble, France., Finas M; Department of Radiology, Grenoble Alpes University Hospital, Grenoble, France., Guillaume B; Department of Radiology, Grenoble Alpes University Hospital, Grenoble, France., Thony F; Department of Radiology, Grenoble Alpes University Hospital, Grenoble, France., Ferretti G; University of Grenoble Alpes, Grenoble, France; Department of Radiology, Grenoble Alpes University Hospital, Grenoble, France., Ghelfi J; University of Grenoble Alpes, Grenoble, France; Department of Radiology, Grenoble Alpes University Hospital, Grenoble, France; INSERM U1209/CNRS UMR 5309, Institute for Advanced Biosciences, University of Grenoble Alpes, Grenoble, France. Electronic address: jghelfi@chu-grenoble.fr.
Jazyk:	angličtina
Zdroj:	Journal of vascular and interventional radiology : JVIR [J Vasc Interv Radiol] 2022 Nov; Vol. 33 (11), pp. 1313-1320. Date of Electronic Publication: 2022 Jul 19.
DOI:	10.1016/j.jvir.2022.07.018
Abstrakt:	Purpose: To evaluate the effectiveness and safety of temporary proximal uterine artery embolization (UAE) for the treatment of highly vascularized retained products of conception (RPOCs). Materials and Methods: This retrospective analysis included women who underwent treatment for vaginal bleeding after abortion, miscarriage, or delivery, with highly vascularized RPOCs detected by Doppler ultrasound (US) (ie, presence of an enhanced myometrial vascularity, a low resistance index of <0.5, and a peak systolic velocity of ≥0.7 m/s). A unilateral or bilateral embolization with torpedoes of gelatin foam was performed. From November 2017 to January 2021, 24 women with a median age of 30 years (interquartile range, 26.0-34.5 years) with symptomatic highly vascularized RPOCs were included. Clinical success was defined as bleeding arrest between the UAE and 1-month follow-up. Technical success was defined as the complete obstruction of at least 1 uterine artery supplying vascular abnormalities. The safety of the procedure according to the classification of the Society of Interventional Radiology and evolution of lesions on US were also reported. Results: Technical success was achieved in all 24 (100%) patients, with bilateral arterial embolization in 19 (79%) patients and unilateral embolization in 5 (21%) patients. Clinical success was achieved in all 24 (100%) patients. Five patients still had uterine retention at the 1-month follow-up, including 2 patients with highly vascularized RPOCs. Two patients benefited from hysteroscopy, and 3 had noninvasive management. Four minor adverse events were reported (1 patient had infectious endometritis and 3 patients had a postembolization syndrome). Conclusions: Proximal UAE with torpedoes of gelatin foam is safe and effective for the management of symptomatic highly vascularized RPOCs. (Copyright © 2022 SIR. Published by Elsevier Inc. All rights reserved.)
Databáze:	MEDLINE
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