Impact of pharmacist intervention on anticoagulation management and risk for potential COVID-19 exposure during the COVID-19 pandemic.

Autor: Lee LC; The Ohio State University General Internal Medicine Clinics, 2050 Kenny Road Suite 2335, Columbus, OH 43221, United States of America; The Ohio State University College of Pharmacy, 500 W. 12th Avenue, Columbus, OH 43210, United States of America. Electronic address: Lee.8791@osu.edu., Farwig P; The Ohio State University General Internal Medicine Clinics, 2050 Kenny Road Suite 2335, Columbus, OH 43221, United States of America. Electronic address: Phillip.Farwig@osumc.edu., Kirk L; The Ohio State University General Internal Medicine Clinics, 2050 Kenny Road Suite 2335, Columbus, OH 43221, United States of America. Electronic address: Lauren.Kirk@osumc.edu., Mitchell VD; The Ohio State University General Internal Medicine Clinics, 2050 Kenny Road Suite 2335, Columbus, OH 43221, United States of America. Electronic address: Virginia.Mitchell@osumc.edu., Sabatino JA; The Ohio State University General Internal Medicine Clinics, 2050 Kenny Road Suite 2335, Columbus, OH 43221, United States of America. Electronic address: Jennifer.Sabatino@osumc.edu., Barnes KD; The Ohio State University General Internal Medicine Clinics, 2050 Kenny Road Suite 2335, Columbus, OH 43221, United States of America. Electronic address: Kelli.Barnes2@osumc.edu.
Jazyk: angličtina
Zdroj: Thrombosis research [Thromb Res] 2022 Sep; Vol. 217, pp. 52-56. Date of Electronic Publication: 2022 Jul 16.
DOI: 10.1016/j.thromres.2022.07.004
Abstrakt: Introduction: Patients taking warfarin require frequent international normalized ratio (INR) monitoring in healthcare settings, putting them at increased risk of Coronavirus disease 2019 (COVID-19) exposure during the pandemic. Thus, strategies to limit in-person visits to healthcare facilities were recommended by the Anticoagulation Forum. The objective of this study was to describe the number and types of changes made to anticoagulation therapy as a result of pharmacist intervention during the COVID-19 pandemic.
Materials and Methods: A retrospective chart review of patients included in a primary care COVID-19 anticoagulation intervention was conducted. During this intervention, pharmacists provided individualized recommendations for anticoagulation changes in patients taking warfarin to limit their healthcare facility exposure while also maintaining safe anticoagulation management practices.
Results: As a result of pharmacist intervention, 83 (55.7 %) of the 149 patients included in the intervention had changes in anticoagulation including: switching to a direct oral anticoagulant (n = 12), extending the INR monitoring interval (n = 48), switching to home INR monitoring (n = 21), or stopping anticoagulation (n = 2). For those patients who were taking warfarin for the entire 6 months pre- and post-intervention, the total number of healthcare facility and laboratory visits with an INR completed decreased from 8.8 to 6.4 (p < 0.001) per patient without a statistically significant decrease in time in therapeutic range (p = 0.76).
Conclusions: This study depicts rapid implementation of a population health-based approach to assess all patients taking warfarin for options to minimize healthcare visits and decrease risk for COVID-19 exposure. Methods to reduce healthcare visit burden while maintaining patient safety should be considered as a regular component of anticoagulation management post-pandemic.
(Copyright © 2022 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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