Autor: |
Mahmud MR; Department of Production Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland., Akter S; Department of Microbiology, Jagannath University, Dhaka, Bangladesh., Tamanna SK; Department of Microbiology, Jagannath University, Dhaka, Bangladesh., Mazumder L; Department of Microbiology, Jagannath University, Dhaka, Bangladesh., Esti IZ; Department of Microbiology, Jagannath University, Dhaka, Bangladesh., Banerjee S; Department of Microbiology, Jagannath University, Dhaka, Bangladesh., Akter S; Department of Microbiology, Jagannath University, Dhaka, Bangladesh., Hasan MR; Department of Microbiology, Jagannath University, Dhaka, Bangladesh., Acharjee M; Department of Bioscience, Graduate School of Science and Technology, Shizuoka University, Shizuoka, Japan., Hossain MS; Institute of Biology, Eötvös Loránd University, Budapest, Hungary., Pirttilä AM; Ecology and Genetics, Faculty of Science, University of Oulu, Oulu, Finland. |
Abstrakt: |
The human intestine hosts diverse microbial communities that play a significant role in maintaining gut-skin homeostasis. When the relationship between gut microbiome and the immune system is impaired, subsequent effects can be triggered on the skin, potentially promoting the development of skin diseases. The mechanisms through which the gut microbiome affects skin health are still unclear. Enhancing our understanding on the connection between skin and gut microbiome is needed to find novel ways to treat human skin disorders. In this review, we systematically evaluate current data regarding microbial ecology of healthy skin and gut, diet, pre- and probiotics, and antibiotics, on gut microbiome and their effects on skin health. We discuss potential mechanisms of the gut-skin axis and the link between the gut and skin-associated diseases, such as psoriasis, atopic dermatitis, acne vulgaris, rosacea, alopecia areata, and hidradenitis suppurativa. This review will increase our understanding of the impacts of gut microbiome on skin conditions to aid in finding new medications for skin-associated diseases. |