Interactions between the κ opioid system, corticotropin-releasing hormone and oxytocin in partner loss.

Autor: Bales KL; Department of Psychology, University of California, Davis, CA 95616, USA.; Department of Neurobiology, Physiology, and Behavior, University of California, Davis, CA 95616, USA.; California National Primate Research Center, Davis, CA 95616, USA., Rogers FD; Princeton Neuroscience Institute, Princeton University, NJ 08540, USA.; Department of Molecular Biology, Princeton University, NJ 08540, USA.
Jazyk: angličtina
Zdroj: Philosophical transactions of the Royal Society of London. Series B, Biological sciences [Philos Trans R Soc Lond B Biol Sci] 2022 Aug 29; Vol. 377 (1858), pp. 20210061. Date of Electronic Publication: 2022 Jul 11.
DOI: 10.1098/rstb.2021.0061
Abstrakt: Selective adult social attachments, or 'pair bonds', represent central relationships for individuals in a number of social species, including humans. Loss of a pair mate has emotional consequences that may or may not diminish over time, and that often translate into impaired psychological and physical health. In this paper, we review the literature on the neuroendocrine mechanisms for the emotional consequences of partner loss, with a special focus on hypothesized interactions between oxytocin, corticotropin-releasing hormone and the κ opioid system. This article is part of the theme issue 'Interplays between oxytocin and other neuromodulators in shaping complex social behaviours'.
Databáze: MEDLINE