Effect of patient gender on short-term blood pressure variability in hemodialysis patients.

Autor: Theodorakopoulou MP; Department of Nephrology, Hippokration Hospital, Aristotle University, Thessaloniki, Greece., Alexandrou ME; Department of Nephrology, Hippokration Hospital, Aristotle University, Thessaloniki, Greece., Karagiannidis AG; Department of Nephrology, Hippokration Hospital, Aristotle University, Thessaloniki, Greece., Geladari V; Department of Nephrology, Hippokration Hospital, Aristotle University, Thessaloniki, Greece., Polychronidou G; Department of Nephrology, Hippokration Hospital, Aristotle University, Thessaloniki, Greece., Papagianni A; Department of Nephrology, Hippokration Hospital, Aristotle University, Thessaloniki, Greece., Sarafidis P; Department of Nephrology, Hippokration Hospital, Aristotle University, Thessaloniki, Greece. psarafidis11@yahoo.gr.
Jazyk: angličtina
Zdroj: Journal of human hypertension [J Hum Hypertens] 2023 Jul; Vol. 37 (7), pp. 519-523. Date of Electronic Publication: 2022 Jul 16.
DOI: 10.1038/s41371-022-00725-6
Abstrakt: Increased blood pressure variability (BPV) is strongly associated with cardiovascular events in end-stage kidney disease patients. Male hemodialysis patients present higher cardiovascular risk compared with females. The aim of this study is to investigate sex differences in short-term BPV in hemodialysis patients. 129 male and 91 female hemodialysis patients that underwent 48-h ABPM were included in this analysis. Standard deviation (SD), weighted SD (wSD), coefficient of variation (CV), and average real variability (ARV) of SBP and DBP were calculated with validated formulas. Age, dialysis vintage and history of major comorbidities did not differ between men and women. 48-h SBP/DBP (137.2 ± 17.4/81.9 ± 12.1 mmHg vs 132.2 ± 19.2/75.9 ± 11.7 mmHg, p = 0.045/<0.001) was significantly higher in men than women. During the 48-h period, all systolic BPV indices were similar between men and women (48-h SBP-ARV: 12.0 ± 2.9 vs 12.1 ± 3.2 mmHg, p = 0.683); 48-h DBP-SD, DBP-wSD and DBP-ARV (9.1 ± 1.6 vs 8.4 ± 1.8 mmHg, p = 0.005) were higher in men. In conclusion, short-term diastolic BPV indices are higher in male than female hemodialysis patients. Increased BPV may impact on the higher incidence of cardiovascular events observed in male hemodialysis patients.
(© 2022. The Author(s), under exclusive licence to Springer Nature Limited.)
Databáze: MEDLINE
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