DCs unchained: Whetting dendritic-cell appetite boosts wound healing.

Autor: Juban G; Institut NeuroMyoGène, Unité Physiopathologie et Génétique du Neurone et du Muscle, Université Claude Bernard Lyon 1, Inserm U1315, CNRS 5261, Lyon, France., Chazaud B; Institut NeuroMyoGène, Unité Physiopathologie et Génétique du Neurone et du Muscle, Université Claude Bernard Lyon 1, Inserm U1315, CNRS 5261, Lyon, France. Electronic address: benedicte.chazaud@inserm.fr.
Jazyk: angličtina
Zdroj: Immunity [Immunity] 2022 Jul 12; Vol. 55 (7), pp. 1156-1158.
DOI: 10.1016/j.immuni.2022.06.008
Abstrakt: Apoptotic-cell uptake (efferocytosis) by dendritic cells (DCs) has been mainly linked to their antigen presentation property. In a recent issue of Nature, Maschalidi et al. identified a break to efferocytosis in DCs, the inhibition of which improves skin debris cleansing after a wound, accelerating healing.
Competing Interests: Declaration of interests The authors declare no competing interests.
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Databáze: MEDLINE