Bullous Pemphigoid: A Spontaneous Presentation in a Patient With Chronic Kidney Disease.
Autor: | Brazen B; Dermatology, Aventura Hospital and Medical Center, Aventura, USA., Kidron A; Emergency Medicine, Nova Southeastern University Kiran C. Patel College of Osteopathic Medicine, Fort Lauderdale, USA., Sheikh Z; Internal Medicine, Aventura Hospital and Medical Center, Aventura, USA., Kamatgi V; Internal Medicine, Aventura Hospital and Medical Center, Aventura, USA., Htoo S; Internal Medicine, Aventura Hospital and Medical Center, Aventura, USA. |
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Jazyk: | angličtina |
Zdroj: | Cureus [Cureus] 2022 Jun 10; Vol. 14 (6), pp. e25806. Date of Electronic Publication: 2022 Jun 10 (Print Publication: 2022). |
DOI: | 10.7759/cureus.25806 |
Abstrakt: | Bullous pemphigoid (BP) is an autoimmune subepidermal blistering pathology characterized by the development of pruritic, tense bullae and blisters on the lower extremities, axilla, and trunk. Its dermatopathology entails autoantibodies that target hemidesmosomes located in the basement membrane. The disease typically manifests in individuals over 50 years old with a higher prevalence in patients with concurrent neurological or dermatological autoimmune diseases. In this report, we discuss a case of a 67-year-old male who presented with a one-month history of itchy blisters occurring bilaterally in the lower extremities. The manifestation of BP, its pathophysiology, and treatment modalities are explored, We also engage in a review of the relevant literature. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2022, Brazen et al.) |
Databáze: | MEDLINE |
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