Characterization of Doppler spectrum of hepatic veins in dogs with pulmonary hypertension.

Autor: Silva VBC; Laboratory of Comparative Cardiology, Department of Veterinary Medicine, Federal University of Paraná, Curitiba, Paraná 80035-050, Brazil. Electronic address: viniciusbcsilva@gmail.com., Froes TR; Department of Veterinary Medicine, Federal University of Paraná, Curitiba, Paraná 80035-050, Brazil., Wolf M; Laboratory of Comparative Cardiology, Department of Veterinary Medicine, Federal University of Paraná, Curitiba, Paraná 80035-050, Brazil., Lucina SB; Laboratory of Comparative Cardiology, Department of Veterinary Medicine, Federal University of Paraná, Curitiba, Paraná 80035-050, Brazil., Sousa MG; Laboratory of Comparative Cardiology, Department of Veterinary Medicine, Federal University of Paraná, Curitiba, Paraná 80035-050, Brazil.
Jazyk: angličtina
Zdroj: Research in veterinary science [Res Vet Sci] 2022 Dec 05; Vol. 150, pp. 131-136. Date of Electronic Publication: 2022 Jul 07.
DOI: 10.1016/j.rvsc.2022.06.021
Abstrakt: Pulmonary hypertension (PH) triggers hemodynamic changes within the right heart, which may affect hepatic venous flow. The aims of this study were three-fold: to investigate, prospectively, the reliability of the hepatic vein Doppler waveform to diagnose and characterize the magnitude of PH in dogs; to evaluate whether a correlation exists between hepatic venous flow waves and the structural and functional characteristics of the right ventricle (RV); and to determine whether age, gender, body weight, heart rate (HR), heart rhythm and systolic blood pressure affect the hepatic venous waveform pattern. A cross-sectional observational study was carried out in 43 dogs with varying degrees of PH and a control group of 15 healthy dogs. The velocities of the hepatic A, S, V and D spectral waves and the phasic pattern varied according to the severity of PH. Weak to moderate correlations were documented between hepatic vein waves and age, HR, and the structural and functional variables of the RV. A D Wave cut-off of 11.6 cm ∙ s-1 had a sensitivity of 100% and specificity of 35% for differentiation of dogs with severe PH from healthy dogs. Doppler assessment of hepatic venous flow was shown to be a reliable technique for screening dogs for PH.
(Copyright © 2022 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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