Thymomas With Intravascular and Intracardiac Growth.
| Autor: | Arrossi AV; Department of Pathology, Robert J. (R.J) Tomsich Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, OH, United States., Dermawan JK; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, United States., Bolen M; Imaging Institute, Cardiovascular and Thoracic Radiology, Cleveland Clinic, Cleveland, OH, United States., Raymond D; Department of Thoracic Surgery, Cleveland Clinic, Cleveland, OH, United States. |
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| Jazyk: | angličtina |
| Zdroj: | Frontiers in oncology [Front Oncol] 2022 Jun 24; Vol. 12, pp. 881553. Date of Electronic Publication: 2022 Jun 24 (Print Publication: 2022). |
| DOI: | 10.3389/fonc.2022.881553 |
| Abstrakt: | Thymomas are derived from the epithelial component of the thymus and constitute the most common tumor of the anterior mediastinum. These neoplasms are considered malignant for their potential for invasion and metastases. Several histopathologic subclassification schemes have been proposed over the years, however, correlation of histotypes with prognosis remains controversial. In contrast, studies invariably have shown that staging and resection status correlate with oncologic behavior and disease outcomes. In this regard, several staging systems have been presented, though transcapsular invasion and degree of involvement of adjacent anatomic structures are common denominators of all schemes. Involvement of the great vessels and heart most commonly results from direct invasion, which may lead to unusual clinical presentations such as superior vena cava syndrome. Moreover, intravascular and intracardiac growth with or without direct mural invasion rarely occurs. We provide an overview of thymomas with intravascular and intracardiac involvement. Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (Copyright © 2022 Arrossi, Dermawan, Bolen and Raymond.) |
| Databáze: | MEDLINE |
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