Retrospective Analysis of Total Parietal Peritonectomy Without Systematic Lymphadenectomy for Advanced Epithelial Ovarian Cancer.

Autor:	Odajima S; Department of Gynecology, National Cancer Center Hospital East, Chiba, Japan., Tanabe H; Department of Gynecology, National Cancer Center Hospital East, Chiba, Japan., Koike Y; Department of Gynecology, National Cancer Center Hospital East, Chiba, Japan., Yokosu K; Department of Gynecology, National Cancer Center Hospital East, Chiba, Japan.
Jazyk:	angličtina
Zdroj:	Cancer diagnosis & prognosis [Cancer Diagn Progn] 2022 Jul 03; Vol. 2 (4), pp. 482-488. Date of Electronic Publication: 2022 Jul 03 (Print Publication: 2022).
DOI:	10.21873/cdp.10131
Abstrakt:	Background/aim: Total parietal peritonectomy (TPP) is a surgical procedure used for complete resection of microscopic peritoneal dissemination. This study analyzed the perioperative complications that developed when omitting systematic lymphadenectomy from TPP. Patients and Methods: We retrospectively analyzed perioperative complications in epithelial ovarian cancer patients with stage IIIB-IVB who underwent TPP during primary and interval cytoreductive surgeries between April 2018 and October 2021. Results: Thirty-three patients were enrolled in the study. The median patient age was 62 years. Of 31 patients (94%) with stage IIIC/IV disease, 24 (73%) had high-grade serous carcinoma. The median operative time and blood loss were 447 min and 2,831 ml, respectively. Complete tumor resection was performed in 30 patients (91%). Only five patients underwent partial lymphadenectomy for clinical metastatic lymph nodes. Further, grade 3 complications were observed in seven (21%) patients, and there were no fatal events in this study. Three patients (9%) had ureteric injuries, which was the most frequent complication in this study. Only one patient developed an intra-abdominal infection due to ascites. In this case, partial para-aortic and pelvic lymphadenectomies were performed. Conclusion: TPP without systematic lymphadenectomy reduces the frequency of perioperative complications associated with ascites. Competing Interests: The Authors declare no conflicts of interest regarding this study. (Copyright 2022, International Institute of Anticancer Research.)
Databáze:	MEDLINE
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