Dengue and Chikungunya virus circulation in Cameroon and Gabon: molecular evidence among symptomatic individuals.

Autor: Djeunang Dongho GB; Laboratory of Immunogenetics, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.; Department of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy., Venturi G; Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy., Fortuna C; Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy., Paganotti GM; Botswana Upenn-Partnership, Gaborone, Botswana.; Division of Infectious Diseases, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Department of Biomedical Sciences, Faculty of Medicine, University of Botswana, Gaborone, Botswana., Severini C; Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy., L'Episcopia M; Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy., Tsapi AT; Department of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy., Benedetti E; Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy., Marsili G; Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy., Amendola A; Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy., Rezza G; Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.; Department of Preventive Health, Ministry of Health, Rome, Italy., Sobze MS; Faculty of Medicine and Pharmaceutical Sciences, University of Dschang, Dschang, Cameroon., Russo G; Department of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy.
Jazyk: angličtina
Zdroj: Access microbiology [Access Microbiol] 2022 Apr 29; Vol. 4 (4), pp. 000340. Date of Electronic Publication: 2022 Apr 29 (Print Publication: 2022).
DOI: 10.1099/acmi.0.000340
Abstrakt: We report the molecular evidence of dengue virus (DENV) and chikungunya virus (CHIKV) infection in symptomatic individuals in Cameroon and Gabon, respectively. Arthropod-borne viruses (arboviruses) are distributed in the tropical or subtropical regions, with DENV having the highest burden. The morbidity and mortality related to arboviral diseases raise the concern of timely and efficient surveillance and care. Our aim was to assess the circulation of arboviruses [DENV, CHIKV, Zika virus (ZIKV)] among febrile patients in Dschang (West Cameroon) and Kyé-ossi (South Cameroon, border with Gabon and Equatorial Guinea). Dried blood spots were collected from 601 consenting febrile patients, and 194 Plasmodium spp.-negative samples were tested for the molecular detection of cases of DENV, CHIKV and ZIKV infection. Overall, no case of ZIKV infection was found, whereas one case of DENV infection and one case of CHIKV infection were detected in Dschang and Kyé-ossi, respectively, with the CHIKV-infected patient being resident in Gabon. Our findings suggest the need to establish an active surveillance of arbovirus transmission in Cameroon and bordering countries.
Competing Interests: The authors declare that there are no conflicts of interest.
(© 2022 The Authors.)
Databáze: MEDLINE