What factors predict craniomandibular disorders in severe COVID-19 survivors after prolonged intubation?

Autor: Pitak-Arnnop P; Department of Oral and Craniomaxillofacial Plastic Surgery, Faculty of Medicine, University Hospital of Giessen and Marburg, UKGM GmbH, Campus Marburg, Philipps-University of Marburg, Marburg, Germany. Electronic address: poramate.pitakarnnop@gmail.com., Tangmanee C; Department of Statistics, Chulalongkorn Business School, Chulalongkorn University, Bangkok, Thailand., Mutirangura W; Department of Occlusion and Accredited Training Center for Dental Occlusion and Orofacial Pain, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand., Apipan B; Division of Anesthesiology, Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Mahidol University, Bangkok, Thailand., Auychai P; Department of Pediatric Dentistry, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand., Meningaud JP; Department of Plastic, Reconstructive, Esthetic and Maxillofacial Surgery, AP-HP, Faculty of Medicine, Henri Mondor University Hospital, University Paris-Est Créteil Val de Marne (Paris XII), Créteil, France., Neff A; Department of Oral and Craniomaxillofacial Plastic Surgery, Faculty of Medicine, University Hospital of Giessen and Marburg, UKGM GmbH, Campus Marburg, Philipps-University of Marburg, Marburg, Germany; Head of the TMJ Section of the Strasbourg Osteosynthesis Research Group (S.O.R.G), Past President of the European Society of TMJ Surgeons (ESTMJS), Member of the German Association for Functional Diagnostics and Therapy of the TMJ (DGFDT) and of the German Association for Oral and Maxillofacial Surgeons (DGMKG), Germany.
Jazyk: angličtina
Zdroj: Journal of stomatology, oral and maxillofacial surgery [J Stomatol Oral Maxillofac Surg] 2022 Nov; Vol. 123 (6), pp. e631-e638. Date of Electronic Publication: 2022 Jul 07.
DOI: 10.1016/j.jormas.2022.07.004
Abstrakt: Purposes: To estimate and identify predictors of craniomandibular disorders (CMDs) in severe COVID-19 survivors after prolonged intubation ≥ 1 week (SCOVIDS-PI).
Methods: This retrospective study enrolled two cohorts of SCOVIDS-PIs with vs. without CMD during a one-year period. The predictor variables were demographic, dental, anesthetic, and laboratory parameters. The main outcome was presence of CMD until six post-PI months (yes/no). Appropriate statistics were computed with α = 95%.
Results: The sample comprised 176 subjects aged 59.2 ± 17.2 years (range, 27-89; 11.9% with CMDs; 30.1% females). CMDs were significantly associated with (1) bilateral posterior tooth loss (P = 0; number needed to screen [NNS] = 1.6), (2) dentofacial skeletal class II/convex face (P = .01; NNS = 2.2), and (3) peak CRP during intensive care ≥ 40 mg/l (P = .01; NNS = 3.5). With combined predictors, NNS became 2 to 4.3.
Conclusions: Three predictors of CMDs in SCOVIDS-PIs: bilateral molar loss, convex face, and CRP ≥ 40 mg/l, indicate CMD screening and/or referral to a CMD specialist, regardless of patients' age, gender, underlying CMDs, or previous dental checkups. Screening ∼2 to 4 "SCOVIDS-PIs with ≥ one predictor" will identify one CMD events/patients during the first six post-PI months.
(Copyright © 2022 Elsevier Masson SAS. All rights reserved.)
Databáze: MEDLINE