| Autor: |
Dheyab MA; School of Physics, Universiti Sains Malaysia, Gelugor 11800, Malaysia.; Nano-Biotechnology Research and Innovation (NanoBRI), Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia, Gelugor 11800, Malaysia., Aziz AA; School of Physics, Universiti Sains Malaysia, Gelugor 11800, Malaysia.; Nano-Biotechnology Research and Innovation (NanoBRI), Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia, Gelugor 11800, Malaysia., Moradi Khaniabadi P; Department of Radiology and Molecular Imaging, College of Medicine and Health Science, Sultan Qaboos University, Muscat 112, Oman., Jameel MS; School of Physics, Universiti Sains Malaysia, Gelugor 11800, Malaysia.; Nano-Biotechnology Research and Innovation (NanoBRI), Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia, Gelugor 11800, Malaysia., Oladzadabbasabadi N; Food Biopolymer Research Group, Food Technology Division, School of Industrial Technology, Universiti Sains Malaysia, Gelugor 11800, Malaysia., Mohammed SA; School of Physics, Universiti Sains Malaysia, Gelugor 11800, Malaysia., Abdullah RS; School of Physics, Universiti Sains Malaysia, Gelugor 11800, Malaysia., Mehrdel B; Department of Physiology and Pharmacology, Thomas J. Long School of Pharmacy & Health Science, University of the Pacific, Stockton, CA 95211, USA. |
| Abstrakt: |
Gold nanoparticles (AuNPs) are becoming increasingly popular as drug carriers due to their unique properties such as size tenability, multivalency, low toxicity and biocompatibility. AuNPs have physical features that distinguish them from bulk materials, small molecules and other nanoscale particles. Their unique combination of characteristics is just now being fully realized in various biomedical applications. In this review, we focus on the research accomplishments and new opportunities in this field, and we describe the rising developments in the use of monodisperse AuNPs for diagnostic and therapeutic applications. This study addresses the key principles and the most recent published data, focusing on monodisperse AuNP synthesis, surface modifications, and future theranostic applications. Moving forward, we also consider the possible development of functionalized monodisperse AuNPs for theranostic applications based on these efforts. We anticipate that as research advances, flexible AuNPs will become a crucial platform for medical applications. |
