The changeable dynamics between glycaemic control and neuropathy risk across the lifespan of Saudi diabetic patients; A survey in diabetes healthcare facility.

Autor: Alfaez SM; Specialist Diabetes and Endocrinology Centre, Prince Mansour Military Hospital, Taif, Saudi Arabia., Alsalmi TI; Specialist Diabetes and Endocrinology Centre, Prince Mansour Military Hospital, Taif, Saudi Arabia., Alfeer RN; Specialist Diabetes and Endocrinology Centre, Prince Mansour Military Hospital, Taif, Saudi Arabia., Alghamdi EK; Specialist Diabetes and Endocrinology Centre, Prince Mansour Military Hospital, Taif, Saudi Arabia., Alzahrani MA; Specialist Diabetes and Endocrinology Centre, Prince Mansour Military Hospital, Taif, Saudi Arabia., Al Bogami SA; Specialist Diabetes and Endocrinology Centre, Prince Mansour Military Hospital, Taif, Saudi Arabia., Mubarak AS; Specialist Diabetes and Endocrinology Centre, Prince Mansour Military Hospital, Taif, Saudi Arabia., Alshehri KM; Specialist Diabetes and Endocrinology Centre, Prince Mansour Military Hospital, Taif, Saudi Arabia., Alfadhly AF; Specialist Diabetes and Endocrinology Centre, Prince Mansour Military Hospital, Taif, Saudi Arabia., AlMalki BM; Specialist Diabetes and Endocrinology Centre, Prince Mansour Military Hospital, Taif, Saudi Arabia., Alosaimi JA; Specialist Diabetes and Endocrinology Centre, Prince Mansour Military Hospital, Taif, Saudi Arabia., Alzahrani FM; Specialist Diabetes and Endocrinology Centre, Prince Mansour Military Hospital, Taif, Saudi Arabia., Al-Ghamdi A; Specialist Diabetes and Endocrinology Centre, Prince Mansour Military Hospital, Taif, Saudi Arabia., Osman M; Armed Forces Center for Psychiatric Care, Taif, Saudi Arabia.
Jazyk: angličtina
Zdroj: Journal of family medicine and primary care [J Family Med Prim Care] 2022 May; Vol. 11 (5), pp. 1745-1747. Date of Electronic Publication: 2022 May 14.
DOI: 10.4103/jfmpc.jfmpc_1362_21
Abstrakt: Background and Aims: Peripheral neuropathy is a common diabetic complication. It is linked to poor glycaemic control and longer duration of diabetes. We explored the association between HbA1c and neuropathy risk considering the duration of diabetes in a sample of Saudi diabetic patients.
Method: We conducted a monofilament test on 343 diabetic patients referred to our specialist diabetology centre in Saudi Arabia. We utilized a multiple generalized logistic regression model with a binary outcome related to neuropathy complications.
Results: We found that over four out of every five patients have peripheral neuropathy. The interaction between HbA1c and duration was significant (estimate = -0.02802, P = 0.00534), a positive association between neuropathy and both HbA1c (increased risk by 46.2%, P = 0.03222) and DM duration (increased risk by 19.6%, P = 0.04497).
Conclusions: The shorter the duration of diabetes, the more positive the relationship between HbA1c and peripheral neuropathy. In patients living for over 40 years with diabetes, HbA1c was higher among those who did not have peripheral neuropathy. It could be argued that this is an artefact of survival as poorer glycaemic control will likely result in higher mortality in earlier years of the diabetes career.
Competing Interests: There are no conflicts of interest.
(Copyright: © 2022 Journal of Family Medicine and Primary Care.)
Databáze: MEDLINE
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje