Incidental Synchronous 99m Tc-HYNIC-TOC Avid Lesion of the Neck in a Patient with Metastatic Melanoma: A Metastatic Lymph Node or a Carotid Body Tumor Masquerading As a Lymph Node?

Autor: Roshanravan V; Nuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran., Soltani E; Surgical Oncology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran., Hasanzadeh Haddad E; Surgical Oncology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran., Sadeghi R; Nuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran., Sahebkari A; Nuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran., Mottaghi M; Student Research Committee, Mashhad University of Medical Sciences, Mashhad, Iran., Aghaee A; Nuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Jazyk: angličtina
Zdroj: Asia Oceania journal of nuclear medicine & biology [Asia Ocean J Nucl Med Biol] 2022 Spring; Vol. 10 (2), pp. 138-141.
DOI: 10.22038/AOJNMB.2021.59706.1415
Abstrakt: A 53-year-old woman with a plantar malignant melanoma lesion was referred to our tertiary clinic for sentinel lymph node mapping. Lymphoscintigraphy with 99m Tc-Phytate detected ipsilateral inguinal and popliteal sentinel nodes. After total resection of nodes, the pathology report confirmed that all specimens were involved by the tumor. As part of an institutional study evaluating somatostatin receptor avidity of melanoma by 99m Tc-HYNIC-TOC scan, she also underwent a whole-body octreotide scan, which surprisingly showed intense tracer uptake in the right cervical region, confining in SPECT/CT images to a mass at the C2 spinal level, adjacent to the right carotid bifurcation. Neck surgery with gamma probe after injection of another dose of 99m Tc-HYNIC-TOC was performed successfully, and the pathology report was consistent with a carotid body tumor. To best our knowledge, our case is the first one in the literature, which reports an incidental paraganglioma with 99m Tc-HYNIC-TOC scan which resected via radio-guided surgery, again with 99m Tc-HYNIC-TOC tracer.
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Databáze: MEDLINE
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