British Society of Gastroenterology guidelines on the management of functional dyspepsia.

Autor:	Black CJ; Leeds Teaching Hospitals NHS Trust, Leeds, UK.; Leeds Institute of Medical Research at St. James's, University of Leeds, Leeds, UK., Paine PA; Division of Diabetes, Endocrinology and Gastroenterology, University of Manchester, Manchester, UK.; Gastroenterology, Salford Royal NHS Foundation Trust, Salford, UK., Agrawal A; Doncaster and Bassetlaw Hospitals NHS Trust, Doncaster, UK., Aziz I; Academic Unit of Gastroenterology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.; Department of Infection, Immunity, and Cardiovascular Disease, University of Sheffield, Sheffield, UK., Eugenicos MP; Department of Gastroenterology, University of Edinburgh, Edinburgh, UK., Houghton LA; Leeds Institute of Medical Research at St. James's, University of Leeds, Leeds, UK., Hungin P; Primary Care and General Practice, University of Newcastle, Newcastle, UK., Overshott R; Greater Manchester Mental Health NHS Foundation Trust, Manchester, UK., Vasant DH; Division of Diabetes, Endocrinology and Gastroenterology, University of Manchester, Manchester, UK.; Neurogastroenterology Unit, Gastroenterology, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester, UK., Rudd S; NIHR Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust, Nottingham, UK.; University of Nottingham and Nottingham Digestive Diseases Centre, School of Medicine, University of Nottingham, Nottingham, UK., Winning RC; NIHR Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust, Nottingham, UK.; University of Nottingham and Nottingham Digestive Diseases Centre, School of Medicine, University of Nottingham, Nottingham, UK., Corsetti M; NIHR Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust, Nottingham, UK.; University of Nottingham and Nottingham Digestive Diseases Centre, School of Medicine, University of Nottingham, Nottingham, UK., Ford AC; Leeds Teaching Hospitals NHS Trust, Leeds, UK alexf12399@yahoo.com.; Leeds Institute of Medical Research at St. James's, University of Leeds, Leeds, UK.
Jazyk:	angličtina
Zdroj:	Gut [Gut] 2022 Sep; Vol. 71 (9), pp. 1697-1723. Date of Electronic Publication: 2022 Jul 07.
DOI:	10.1136/gutjnl-2022-327737
Abstrakt:	Functional dyspepsia (FD) is a common disorder of gut-brain interaction, affecting approximately 7% of individuals in the community, with most patients managed in primary care. The last British Society of Gastroenterology (BSG) guideline for the management of dyspepsia was published in 1996. In the interim, substantial advances have been made in understanding the complex pathophysiology of FD, and there has been a considerable amount of new evidence published concerning its diagnosis and classification, with the advent of the Rome IV criteria, and management. The primary aim of this guideline, commissioned by the BSG, is to review and summarise the current evidence to inform and guide clinical practice, by providing a practical framework for evidence-based diagnosis and treatment of patients. The approach to investigating the patient presenting with dyspepsia is discussed, and efficacy of drugs in FD summarised based on evidence derived from a comprehensive search of the medical literature, which was used to inform an update of a series of pairwise and network meta-analyses. Specific recommendations have been made according to the Grading of Recommendations Assessment, Development and Evaluation system. These provide both the strength of the recommendations and the overall quality of evidence. Finally, in this guideline, we consider novel treatments that are in development, as well as highlighting areas of unmet need and priorities for future research. Competing Interests: Competing interests: None declared. (© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)
Databáze:	MEDLINE
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