Ready for regulatory use: NAMs and NGRA for chemical safety assurance.

Autor:	Carmichael PL; Safety & Environmental Assurance Centre (SEAC), Unilever, Sharnbrook, Bedfordshire, UK.; Toxicology, Wageningen University & Research, Wageningen, The Netherlands., Baltazar MT; Safety & Environmental Assurance Centre (SEAC), Unilever, Sharnbrook, Bedfordshire, UK., Cable S; Safety & Environmental Assurance Centre (SEAC), Unilever, Sharnbrook, Bedfordshire, UK., Cochrane S; Safety & Environmental Assurance Centre (SEAC), Unilever, Sharnbrook, Bedfordshire, UK., Dent M; Safety & Environmental Assurance Centre (SEAC), Unilever, Sharnbrook, Bedfordshire, UK., Li H; Safety & Environmental Assurance Centre (SEAC), Unilever, Sharnbrook, Bedfordshire, UK., Middleton A; Safety & Environmental Assurance Centre (SEAC), Unilever, Sharnbrook, Bedfordshire, UK., Muller I; Safety & Environmental Assurance Centre (SEAC), Unilever, Sharnbrook, Bedfordshire, UK., Reynolds G; Safety & Environmental Assurance Centre (SEAC), Unilever, Sharnbrook, Bedfordshire, UK., Westmoreland C; Safety & Environmental Assurance Centre (SEAC), Unilever, Sharnbrook, Bedfordshire, UK., White A; Safety & Environmental Assurance Centre (SEAC), Unilever, Sharnbrook, Bedfordshire, UK.
Jazyk:	angličtina
Zdroj:	ALTEX [ALTEX] 2022; Vol. 39 (3), pp. 359–366. Date of Electronic Publication: 2022 Jul 04.
DOI:	10.14573/altex.2204281
Abstrakt:	New approach methodologies (NAMs) that do not use experimental animals are, in certain settings, entirely appropriate for assuring the safety of chemical ingredients, although regulatory adoption has been slow. In this opinion article we discuss how scientific advances that utilize NAMs to certify systemic safety are available now and merit broader acceptance within the framework of next generation risk assessments (NGRA).
Databáze:	MEDLINE
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