Down syndrome: a review of ocular manifestations.

Autor:	Haseeb A; Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, IL, USA., Huynh E; Department of Ophthalmology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA., ElSheikh RH; Department of Ophthalmology, Kasr Al-Ainy Hospitals, Cairo University, Cairo, Egypt., ElHawary AS; Qena Faculty of Medicine, South Valley, Egypt., Scelfo C; Department of Ophthalmology, Boston Children's Hospital, Hawthorne, NY, USA., Ledoux DM; Department of Ophthalmology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA., Maidana DE; Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, IL, USA., Elhusseiny AM; Department of Ophthalmology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Jazyk:	angličtina
Zdroj:	Therapeutic advances in ophthalmology [Ther Adv Ophthalmol] 2022 Jun 30; Vol. 14, pp. 25158414221101718. Date of Electronic Publication: 2022 Jun 30 (Print Publication: 2022).
DOI:	10.1177/25158414221101718
Abstrakt:	Down syndrome is the most common genetically mediated intellectual disability. Although many physiologic and pathologic features of Down syndrome are discussed at length in the literature, the ocular manifestations of Down syndrome have seldom been discussed in a comprehensive fashion. Given that Down syndrome has ocular manifestations from the front to the back of the eye, it is important for physicians to become familiar with these manifestations, especially given the prevalence of Down syndrome. This review aims to discuss the varied ophthalmologic manifestations of Down syndrome - including strabismus, amblyopia, nystagmus, accommodation deficits, nasolacrimal duct obstruction, keratoconus, optic nerve pathology, neoplastic disease, and retinal pathology - to facilitate better care and visual outcomes in this important patient population. Competing Interests: Conflict of interest statement: The authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article. (© The Author(s), 2022.)
Databáze:	MEDLINE
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