Prevalence of primary angle-closure disease in retinitis pigmentosa.

Autor: Pradhan ZS; Department of Glaucoma, Narayana Nethralaya, Bengaluru, Karnataka, India., Shroff S; Department of Glaucoma, Narayana Nethralaya, Bengaluru, Karnataka, India., Bansod A; Department of Glaucoma, Narayana Nethralaya, Bengaluru, Karnataka, India., Poornachandra B; Department of Retina, Narayana Nethralaya, Bengaluru, Karnataka, India., Shetty A; Department of Glaucoma, Narayana Nethralaya, Bengaluru, Karnataka, India., Devi S; Department of Glaucoma, Narayana Nethralaya, Bengaluru, Karnataka, India., Rao DAS; Department of Glaucoma, Narayana Nethralaya, Bengaluru, Karnataka, India., Puttaiah NK; Department of Glaucoma, Narayana Nethralaya, Bengaluru, Karnataka, India., Rao HL; Department of Glaucoma, Narayana Nethralaya, Bengaluru, Karnataka, India.
Jazyk: angličtina
Zdroj: Indian journal of ophthalmology [Indian J Ophthalmol] 2022 Jul; Vol. 70 (7), pp. 2449-2451.
DOI: 10.4103/ijo.IJO_3189_21
Abstrakt: Purpose: To determine the prevalence of primary angle-closure disease (PACD) in patients with retinitis pigmentosa (RP).
Methods: This was a retrospective review of the electronic medical records of all RP patients over the age of 10 years attending the Genetics Eye Clinic of a tertiary-care hospital during a 7-year period. Information regarding age, gender, vision, refraction, lens, intraocular pressure (IOP), type of RP, and inheritance pattern using pedigree charts for all patients were obtained. Patients with a shallow anterior chamber, high IOP, or glaucomatous optic discs were referred to the glaucoma department where they underwent additional IOP measurements, a gonioscopy, and disc evaluation by a glaucoma specialist. The prevalence of PACD was determined.
Results: A total of 618 RP patients were examined during the study period, of which 95.1% had typical RP. The prevalence of primary angle-closure suspects was 2.9%, primary angle closure was 0.65%, and primary angle-closure glaucoma (PACG) was 2.27%. In contrast, the prevalence of primary open-angle glaucoma was 1.29%. The prevalence of PACG in those older than 40 years was 3.8% (95% confidence interval: 1.6-6.0).
Conclusion: The prevalence of PACG in RP patients over 40 years was higher than that found in the general population of a similar age (3.8% vs. 0.8%). In our cohort of RP patients, 5.9% had PACD. Hence, gonioscopy is warranted in all RP patients to identify this condition and treat it appropriately.
Competing Interests: None
Databáze: MEDLINE
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