Characterization of IG-MYC-breakpoints and their application for quantitative minimal disease monitoring in high-risk pediatric Burkitt-lymphoma and -leukemia.

Autor: Möker P; Pediatric Hematology and Oncology and NHL-BFM Study Center, University Medical Center Hamburg-Eppendorf, 20246, Hamburg, Germany., Zur Stadt U; Pediatric Hematology and Oncology and CoALL Study Center, University Medical Center Hamburg-Eppendorf, 20246, Hamburg, Germany., Zimmermann M; Department of Pediatric Hematology and Oncology, Hannover Medical School, and NHL-BFM Study Center, Hannover, Germany., Alawi M; Bioinformatics Core, University Medical Center Hamburg-Eppendorf, 20246, Hamburg, Germany., Mueller S; Pediatric Hematology and Oncology and NHL-BFM study Center, University Hospital Muenster, Muenster, Germany., Finger J; Pediatric Hematology and Oncology and NHL-BFM study Center, University Hospital Muenster, Muenster, Germany., Knörr F; Pediatric Hematology and Oncology and NHL-BFM Study Center, University Medical Center Hamburg-Eppendorf, 20246, Hamburg, Germany.; Mildred Scheel Cancer Career Center HaTriCS4, University Medical Center Hamburg- Eppendorf, Hamburg, Germany., Riquelme A; Pediatric Hematology and Oncology and NHL-BFM Study Center, University Medical Center Hamburg-Eppendorf, 20246, Hamburg, Germany., Oschlies I; Department of Pathology, Hematopathology Section and Lymph Node Registry, University Hospital Schleswig-Holstein, Campus Kiel/Christian-Albrechts-University, Kiel, Germany., Klapper W; Department of Pathology, Hematopathology Section and Lymph Node Registry, University Hospital Schleswig-Holstein, Campus Kiel/Christian-Albrechts-University, Kiel, Germany., Bradtke J; Department of Pathology, Justus-Liebig-University, Giessen, Germany., Burkhardt B; Pediatric Hematology and Oncology and NHL-BFM study Center, University Hospital Muenster, Muenster, Germany., Woessmann W; Pediatric Hematology and Oncology and NHL-BFM Study Center, University Medical Center Hamburg-Eppendorf, 20246, Hamburg, Germany. w.woessmann@uke.de., Damm-Welk C; Pediatric Hematology and Oncology and NHL-BFM Study Center, University Medical Center Hamburg-Eppendorf, 20246, Hamburg, Germany. c.damm-welk@uke.de.
Jazyk: angličtina
Zdroj: Leukemia [Leukemia] 2022 Sep; Vol. 36 (9), pp. 2343-2346. Date of Electronic Publication: 2022 Jul 05.
DOI: 10.1038/s41375-022-01626-w
Databáze: MEDLINE