Preoperative localisation of nonpalpable breast lesions using magnetic markers in a tertiary cancer centre.

Autor: Petrillo A; Radiology Division, 'Istituto Nazionale Tumori-IRCCS Fondazione G. Pascale', Naples, Italy. a.petrillo@istitutotumori.na.it., Di Giacomo R; Breast Surgery Division, 'Istituto Nazionale Tumori-IRCCS-Fondazione G. Pascale', Naples, Italy., Esposito E; Breast Surgery Division, 'Istituto Nazionale Tumori-IRCCS-Fondazione G. Pascale', Naples, Italy., Vallone P; Radiology Division, 'Istituto Nazionale Tumori-IRCCS Fondazione G. Pascale', Naples, Italy., Setola SV; Radiology Division, 'Istituto Nazionale Tumori-IRCCS Fondazione G. Pascale', Naples, Italy., Raso MM; Radiology Division, 'Istituto Nazionale Tumori-IRCCS Fondazione G. Pascale', Naples, Italy., Granata V; Radiology Division, 'Istituto Nazionale Tumori-IRCCS Fondazione G. Pascale', Naples, Italy., Barretta ML; Radiology Division, 'Istituto Nazionale Tumori-IRCCS Fondazione G. Pascale', Naples, Italy., Siani C; Breast Surgery Division, 'Istituto Nazionale Tumori-IRCCS-Fondazione G. Pascale', Naples, Italy., Rinaldo C; Division of Radiology - Presidio Ospedaliero di Marcianise, Caserta, Italy., Donzelli I; Breast Surgery Division, 'Istituto Nazionale Tumori-IRCCS-Fondazione G. Pascale', Naples, Italy., Marone U; Breast Surgery Division, 'Istituto Nazionale Tumori-IRCCS-Fondazione G. Pascale', Naples, Italy., Melucci MT; Breast Surgery Division, 'Istituto Nazionale Tumori-IRCCS-Fondazione G. Pascale', Naples, Italy., Fucito A; Breast Surgery Division, 'Istituto Nazionale Tumori-IRCCS-Fondazione G. Pascale', Naples, Italy., Saponara R; Breast Surgery Division, 'Istituto Nazionale Tumori-IRCCS-Fondazione G. Pascale', Naples, Italy., Di Bonito M; Pathology Division, 'Istituto Nazionale Tumori-IRCCS-Fondazione G. Pascale', Naples, Italy., Fusco R; Medical Oncology Division, Igea SpA, Naples, Italy., Rinaldo M; Breast Surgery Division, 'Istituto Nazionale Tumori-IRCCS-Fondazione G. Pascale', Naples, Italy., Avino F; Breast Surgery Division, 'Istituto Nazionale Tumori-IRCCS-Fondazione G. Pascale', Naples, Italy.
Jazyk: angličtina
Zdroj: European radiology experimental [Eur Radiol Exp] 2022 Jul 06; Vol. 6 (1), pp. 28. Date of Electronic Publication: 2022 Jul 06.
DOI: 10.1186/s41747-022-00280-2
Abstrakt: Background: We retrospectively evaluated safety and performance of magnetic seed localisation of nonpalpable breast lesions.
Methods: We reviewed records of patients with nonpalpable breast lesions preoperative localised by placing magnetic Magseed® marker between February 2019 and December 2020. During surgery, Sentimag® magnetic probe was used to localise the marker and guide surgery. Safety, lesion identification and excision with tumour with free margins and re-excision rate were assessed.
Results: A total of 77 Magseed® devices were placed into the breasts of 73 patients, 44 under ultrasound and 33 under stereotactic guidance (4 bilateral). All devices were retrieved as were the target lesions. Magnetic marker placement was successful in all cases without any adverse event. Intraoperative identification and excision of the localised lesion were successful in 77 of 77 of cases (100%). In three cases (all of them calcifications with the seed placed under stereotactic guidance), the seed did not reach the exact target position of the biopsy clip; thus, larger excision was needed, with localisation failure attributed to incorrect clip insertion (n = 1) or to clip dislocation (n = 2). Migration of the marker was negligible in all patients. Complete excision after the initial procedure with at least 1-mm disease-free margins was obtained in 74 out of 77 (96.1%) lesions. The re-excision rate was 3 out of 77 (4%).
Conclusions: Magnetic marker localisation for nonpalpable breast lesions was safe, reliable, and effective in terms of lesion identification, excision with tumour-free margins and re-excision rate.
(© 2022. The Author(s) under exclusive licence to European Society of Radiology.)
Databáze: MEDLINE
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