Autor:	Zhang X, Englund DA, Aversa Z, Jachim SK; Mayo Clinic Graduate School of Biomedical Sciences., White TA; Robert and Arlene Kogod Center on Aging., LeBrasseur NK
Jazyk:	angličtina
Zdroj:	Exercise and sport sciences reviews [Exerc Sport Sci Rev] 2022 Oct 01; Vol. 50 (4), pp. 213-221. Date of Electronic Publication: 2022 Jul 01.
DOI:	10.1249/JES.0000000000000302
Abstrakt:	We propose the beneficial effects of exercise are in part mediated through the prevention and elimination of senescent cells. Exercise counters multiple forms of age-related molecular damage that initiate the senescence program and activates immune cells responsible for senescent cell clearance. Preclinical and clinical evidence for exercise as a senescence-targeting therapy and areas needing further investigation are discussed. (Copyright © 2022 by the American College of Sports Medicine.)
Databáze:	MEDLINE
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