Microalgae-derived polysaccharides: Potential building blocks for biomedical applications.

Autor: Severo IA; Sustainable Energy Research and Development Center (NPDEAS), Federal University of Paraná (UFPR), P.O. Box 19011, Curitiba, PR, 81531-980, Brazil. ihana.aguiar@gmail.com., Dias RR; Department of Food Science and Technology, Federal University of Santa Maria (UFSM), Roraima Avenue, 1000, Santa Maria, RS, 97105-900, Brazil., do Nascimento TC; Department of Food Science and Technology, Federal University of Santa Maria (UFSM), Roraima Avenue, 1000, Santa Maria, RS, 97105-900, Brazil., Deprá MC; Department of Food Science and Technology, Federal University of Santa Maria (UFSM), Roraima Avenue, 1000, Santa Maria, RS, 97105-900, Brazil., Maroneze MM; Department of Food Science and Technology, Federal University of Santa Maria (UFSM), Roraima Avenue, 1000, Santa Maria, RS, 97105-900, Brazil., Zepka LQ; Department of Food Science and Technology, Federal University of Santa Maria (UFSM), Roraima Avenue, 1000, Santa Maria, RS, 97105-900, Brazil., Jacob-Lopes E; Department of Food Science and Technology, Federal University of Santa Maria (UFSM), Roraima Avenue, 1000, Santa Maria, RS, 97105-900, Brazil.
Jazyk: angličtina
Zdroj: World journal of microbiology & biotechnology [World J Microbiol Biotechnol] 2022 Jul 01; Vol. 38 (9), pp. 150. Date of Electronic Publication: 2022 Jul 01.
DOI: 10.1007/s11274-022-03342-0
Abstrakt: In recent years, the increasing concern about human health well-being has strongly boosted the search for natural alternatives that can be used in different fields, especially in biomedicine. This has put microalgae-based products in evidence since they contain many bioactive compounds, of which polysaccharides are attractive due to the diverse physicochemical properties and new or improved biological roles they play. Polysaccharides from microalgae, specially exopolysaccharides, are critically important for market purposes because they can be used as anti-inflammatory, immunomodulatory, anti-glycemic, antitumor, antioxidant, anticoagulant, antilipidemic, antiviral, antibacterial, and antifungal agents. Therefore, to obtain higher productivity and competitiveness of these naturally available compounds, the cultivation parameters and the extraction/purification processes must be better optimized in order to bring perspectives for the exploitation of products in commercial and clinical practice. In this sense, the objective of the present review is to elucidate the potential biomedical applications of microalgae-derived polysaccharides. A closer look is taken at the main polysaccharides produced by microalgae, methods of extraction, purification and structural determination, biological activities and their applications, and current status.
(© 2022. The Author(s), under exclusive licence to Springer Nature B.V.)
Databáze: MEDLINE
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