STI prevalence, incidence, and partner notification among women in a periconception HIV prevention program in Uganda.

Autor:	Chitneni P; Division of Infectious Diseases, 2348Massachusetts General Hospital, Boston, MA, USA.; Division of Infectious Diseases and General Internal Medicine, 1861Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Muyindike W; 108123Mbarara Regional Referral Hospital and Mbarara University of Science and Technology, Mbarara, Uganda., Bwana MB; 108123Mbarara Regional Referral Hospital and Mbarara University of Science and Technology, Mbarara, Uganda., Owembabazi M; 108123Mbarara Regional Referral Hospital and Mbarara University of Science and Technology, Mbarara, Uganda., O'Neil K; Division of Infectious Diseases, 2348Massachusetts General Hospital, Boston, MA, USA.; Mbarara University of Science and Technology Global Health Collaborative, Mbarara, Uganda., Kalyebara PK; 108123Mbarara Regional Referral Hospital and Mbarara University of Science and Technology, Mbarara, Uganda., Hedt-Gauthier B; Department of Global Health and Social Medicine, 1811Harvard Medical School, Boston, MA, USA., Bangsberg DR; 143856OHSU PSU School of Public Health, Portland, OR, USA., Marrazzo JM; Division of Infectious Diseases, 9968University of Alabama, Birmingham, AL, USA., Kaida A; 1763Simon Fraser University, Burnaby, British Columbia, Canada., Haberer JE; Harvard Medical School, Boston, MA, USA.; 108123Mbarara Regional Referral Hospital and Mbarara University of Science and Technology, Mbarara, Uganda.; Center for Global Health, 2348Massachusetts General Hospital, Boston, MA, USA., Matthews LT; Division of Infectious Diseases, 9968University of Alabama, Birmingham, AL, USA.
Jazyk:	angličtina
Zdroj:	International journal of STD & AIDS [Int J STD AIDS] 2022 Aug; Vol. 33 (9), pp. 856-863. Date of Electronic Publication: 2022 Jun 30.
DOI:	10.1177/09564624221110992
Abstrakt:	Background: We provided sexually transmitted infection (STI) screening and facilitated partner notification and treatment among women participating in a periconception HIV prevention program in southwestern Uganda to understand follow-up STI incidence. Methods: Women at-risk for HIV exposure while planning for pregnancy completed laboratory screening for chlamydia, gonorrhea, trichomoniasis, and syphilis at enrollment and 6 months of follow-up and/or incident pregnancy; facilitated partner notification and treatment were offered for those with positive tests. We performed a logistic regression to determine correlates of follow-up STI. Results: Ninety-four participants completed enrollment STI screening with a median age of 29 (IQR 26-34); 23 (24%) had ≥1 STI. Of the 23 participants with enrollment STI(s), all completed treatment and 19 (83%) returned for follow-up; 18 (78%) reported delivering partner notification cards and discussing STIs with partner(s), and 14 (61%) reported all partners received STI treatment. Of the 81 (86%) who successfully completed follow-up STI screening, 17 (21%) had ≥1 STI. The STI incidence rate was 29.0 per 100 person-years. In univariable regression analysis, enrollment STI, younger age, less education, and alcohol consumption were all significantly associated with follow-up STI. Conclusions: We demonstrated high enrollment and follow-up STI rates and moderate participant-reported partner treatment among women planning for pregnancy in Uganda despite partner notification and treatment. Novel STI partner notification and treatment interventions are needed to decrease the STI burden, especially among women planning for and with pregnancy.
Databáze:	MEDLINE
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