| Autor: |
Peter CD; Gastroenterology, First Affiliated Hospital. China Medical University, china., Huang YH; Gastroenterology, First Affiliated Hospital. China Medical University., Tian WN; Gastroenterology, First Affiliated Hospital. China Medical University. |
| Jazyk: |
angličtina |
| Zdroj: |
Revista espanola de enfermedades digestivas [Rev Esp Enferm Dig] 2022 Dec; Vol. 114 (12), pp. 757-758. |
| DOI: |
10.17235/reed.2022.8964/2022 |
| Abstrakt: |
It is difficult to manage UC patients with tumor and extraintestinal manifestations (EIMs). We present this case of acute severe UC patient with peripheral arthritis and orbital tumor could be successfully managed by the concomitant use of two biologics (Dual targeted therapy, DTT) including vedolizumab (VDZ) and ustekinumab (UST). VDZ is approved for the treatment of patients with moderate-to-severe UC, but might have limited efficacy in treating EIMs due to its gut specific mechanism. UST shows clinical efficacy in the treatment of EIMs and is used for UC treatment. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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