Aging and macrophages: Not standing the test of time?

Autor: Sureshchandra S; Institute for Immunology, University of California, Irvine, California, USA.; Department of Physiology and Biophysics, University of California, Irvine, California, USA., Messaoudi I; Department of Microbiology, Immunology, and Molecular Genetics, College of Medicine, University of Kentucky, Lexington, Kentucky, USA.
Jazyk: angličtina
Zdroj: Journal of leukocyte biology [J Leukoc Biol] 2022 Dec; Vol. 112 (6), pp. 1369-1370. Date of Electronic Publication: 2022 Jun 29.
DOI: 10.1002/JLB.3CE0322-145R
Abstrakt: The underlying mechanism of immunosenescence and compromised responses to environmental stressors in alveolar macrophages is a result of epigenetic dysregulation, rather than loss of subtypes.
(©2022 Society for Leukocyte Biology.)
Databáze: MEDLINE