Unprecedented frequency of mitochondrial introns in colonial bilaterians.

Autor: Jenkins HL; Department of Life Sciences, Natural History Museum, Cromwell Road, London, SW7 5BD, UK. helen.jenkins@nhm.ac.uk.; Marine Biological Association, The Laboratory, Citadel Hill, Plymouth, PL1 2PB, Devon, UK. helen.jenkins@nhm.ac.uk., Graham R; Department of Life Sciences, Natural History Museum, Cromwell Road, London, SW7 5BD, UK., Porter JS; Department of Life Sciences, Natural History Museum, Cromwell Road, London, SW7 5BD, UK.; International Centre Island Technology, Heriot Watt University, Orkney Campus, Robert Rendall Building, Franklin Road, Stromness, Orkney, KW16 3AW, Scotland, UK., Vieira LM; Department of Life Sciences, Natural History Museum, Cromwell Road, London, SW7 5BD, UK.; Laboratório de Estudos de Bryozoa-LAEBry, Departamento de Zoologia, Centro de Biociências, Universidade Federal de Pernambuco, Recife, PE, 50670-901, Brazil., de Almeida ACS; Laboratório de Estudos de Bryozoa-LAEBry, Departamento de Zoologia, Centro de Biociências, Universidade Federal de Pernambuco, Recife, PE, 50670-901, Brazil.; Museu de História Natural, Setor da Zoologia, Universidade Federal da Bahia, Salvador, BA, 40170-115, Brazil., Hall A; Core Research Labs, Natural History Museum, Cromwell Road, London, SW7 5BD, UK., O'Dea A; Smithsonian Tropical Research Institute, Balboa, Ancon, Republic of Panama., Coppard SE; Bader International Study Centre, Queen's University (Canada), Herstmonceux Castle, Hailsham, BN27 1RN, East Sussex, UK., Waeschenbach A; Department of Life Sciences, Natural History Museum, Cromwell Road, London, SW7 5BD, UK. a.waeschenbach@nhm.ac.uk.
Jazyk: angličtina
Zdroj: Scientific reports [Sci Rep] 2022 Jun 28; Vol. 12 (1), pp. 10889. Date of Electronic Publication: 2022 Jun 28.
DOI: 10.1038/s41598-022-14477-3
Abstrakt: Animal mitogenomes are typically devoid of introns. Here, we report the largest number of mitochondrial introns ever recorded from bilaterian animals. Mitochondrial introns were identified for the first time from the phylum Bryozoa. They were found in four species from three families (Order Cheilostomatida). A total of eight introns were found in the complete mitogenome of Exechonella vieirai, and five, 17 and 18 introns were found in the partial mitogenomes of Parantropora penelope, Discoporella cookae and Cupuladria biporosa, respectively. Intron-encoded protein domains reverse transcriptase and intron maturase (RVT-IM) were identified in all species. Introns in E. vieirai and P. penelope had conserved Group II intron ribozyme domains V and VI. Conserved domains were lacking from introns in D. cookae and C. biporosa, preventing their further categorization. Putative origins of metazoan introns were explored in a phylogenetic context, using an up-to-date alignment of mitochondrial RVT-IM domains. Results confirmed previous findings of multiple origins of annelid, placozoan and sponge RVT-IM domains and provided evidence for common intron donor sources across metazoan phyla. Our results corroborate growing evidence that some metazoans with regenerative abilities (i.e. placozoans, sponges, annelids and bryozoans) are susceptible to intron integration, most likely via horizontal gene transfer.
(© 2022. Crown.)
Databáze: MEDLINE
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