Oral Malignant Melanoma in a Patient With Neurofibromatosis Type 1: An Extremely Rare Association.

Autor:	Berhili S; Faculty of Medicine and Pharmacy, Mohammed First University, Oujda, MAR.; Departement of Radiation Oncology, Hassan II Oncology Centre, Mohammed VI University Hospital, Oujda, MAR., Rezzoug M; Department of Radiation Oncology, Hassan II Oncology Centre, Mohammed VI University Hospital, Oujda, MAR.; LPMR, Faculty of Sciences, Mohammed Premier University, Oujda, MAR., Ben Sghier A; Department of Radiation Oncology, Hassan II Oncology Centre, Mohammed VI University Hospital, Oujda, MAR., Moukhlissi M; Department of Radiation Oncology, Hassan II Oncology Centre, Mohammed VI University Hospital, Oujda, MAR.; Faculty of Medicine and Pharmacy, Mohammed Premier University, Oujda, MAR., Mezouar L; Department of Radiation Oncology, Hassan II Oncology Centre, Mohammed VI University Hospital, Oujda, MAR.; Faculty of Medicine and Pharmacy, Mohammed Premier University, Oujda, MAR.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2022 May 25; Vol. 14 (5), pp. e25331. Date of Electronic Publication: 2022 May 25 (Print Publication: 2022).
DOI:	10.7759/cureus.25331
Abstrakt:	Neurofibromatosis type 1 (NF1) is a genetic disorder associated with high rates of neural crest-derived tumors, both benign and malignant. Many series have identified cutaneous melanoma as a rare tumor among cancers occurring in individuals with NF1 disease, but the mucosal location has to date never been reported. In this paper, we report an oral melanoma occurring in a patient with NF1 disorder, diagnosed at a locally advanced stage, successfully managed by definitive external beam radiotherapy, along with a comprehensive literature review on the melanoma-NF1 association. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2022, Berhili et al.)
Databáze:	MEDLINE
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