[A case of polyneuropathy after COVID-19 vaccine].

Autor: Iseki M; Department of Neurology, Tokyo Metropolitan Bokutoh Hospital., Nakayama H; Department of Neurology, Tokyo Metropolitan Bokutoh Hospital., Watanabe M; Department of Neurology, Tokyo Metropolitan Bokutoh Hospital., Uchibori A; Department of Neurology, Kyorin University Hospital., Chiba A; Department of Neurology, Kyorin University Hospital., Mizutani S; Department of Neurology, Tokyo Metropolitan Bokutoh Hospital.
Jazyk: japonština
Zdroj: Rinsho shinkeigaku = Clinical neurology [Rinsho Shinkeigaku] 2022 Jul 29; Vol. 62 (7), pp. 558-562. Date of Electronic Publication: 2022 Jun 24.
DOI: 10.5692/clinicalneurol.cn-001750
Abstrakt: A 43-year-old-woman developed paresthesia, weakness of limbs, dysphagia and deep sensory impairment 12 days after vaccination of Pfizer COVID-19 vaccine. Her deep tendon reflexes were absent and cerebrospinal fluid showed normal cell counts and protein level. Anti-ganglioside antibodies were negative, and F wave frequency was decreased in nerve conduction studies. We diagnosed her as immune mediated polyneuropathy caused by COVID-19 vaccine, and plasma exchange improved her symptoms. Compared with Guillain-Barré syndrome and polyneuropathy following COVID-19 infection and COVID-19 vaccination, deep sensory impairment was the most characteristic of this case. We supposed that non-antigen specific mechanism played an important role in the pathogenesis of this case.
Databáze: MEDLINE