Depression in Sub-Saharan Africa.
| Autor: | Gbadamosi IT; Department of Anatomy, University of Ilorin, Nigeria.; Laboratory for Translational Research in Neuropsychiatric Disorders, BRAINCITY Nencki-EMBL Center of Excellence for Neural Plasticty and Brain Disorders, Warsaw, Poland., Henneh IT; Department of Pharmacotherapeutics and Pharmacy Practice, School of Pharmacy and Pharmaceutical Sciences, University of Cape Coast, Ghana., Aluko OM; Department of Physiology, School of Basic Medical Sciences, Federal University of Technology, Akure, Nigeria., Yawson EO; Department of Anatomy Redeemer's University, Nigeria., Fokoua AR; Department of Animal Biology University of Dschang, Cameroon., Koomson A; Department of Pharmacology and Toxicology University of Ghana, Ghana., Torbi J; Department of Pharmacology and Toxicology University of Ghana, Ghana., Olorunnado SE; Department of Anatomy, Kogi State University, Nigeria., Lewu FS; Department of Anatomy, University of Ilorin, Nigeria., Yusha'u Y; Department of Human Physiology Ahmadu Bello University, Zaria, Nigeria., Keji-Taofik ST; Department of Anatomy, University of Ilorin, Nigeria., Biney RP; Department of Pharmacotherapeutics and Pharmacy Practice, School of Pharmacy and Pharmaceutical Sciences, University of Cape Coast, Ghana., Tagoe TA; Physiology Department, University of Ghana, Ghana. |
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| Jazyk: | angličtina |
| Zdroj: | IBRO neuroscience reports [IBRO Neurosci Rep] 2022 Mar 17; Vol. 12, pp. 309-322. Date of Electronic Publication: 2022 Mar 17 (Print Publication: 2022). |
| DOI: | 10.1016/j.ibneur.2022.03.005 |
| Abstrakt: | Mood disorders can be considered among the most common and debilitating mental disorders. Major depression, as an example of mood disorders, is known to severely reduce the quality of life as well as psychosocial functioning of those affected. Its impact on the burden of disease worldwide has been enormous, with the World Health Organisation projecting depression to be the leading cause of mental illness by 2030. Despite several studies on the subject, little has been done to contextualise the condition in Africa, coupled with the fact that there is still much to be understood on the subject. This review attempts to shed more light on the prevalence of depression in Sub-Saharan Africa (SSA), its pathophysiology, risk factors, diagnosis and the experimental models available to study depression within the sub-region. It also evaluates the contribution of the sub-region to the global research output of depression as well as bottlenecks associated with full exploitation of the sub region's resources to manage the disorder. Competing Interests: There are no conflicts of interest to declare. (© 2022 The Authors.) |
| Databáze: | MEDLINE |
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