Trichoderma Enzymes for Degradation of Aflatoxin B1 and Ochratoxin A.

Autor: Dini I; Department of Pharmacy, University of Naples Federico II, Via Domenico Montesano 49, 80131 Naples, Italy., Alborino V; Department of Agricultural Sciences, University of Naples Federico II, Via Università 100, 80055 Portici, Italy., Lanzuise S; Department of Agricultural Sciences, University of Naples Federico II, Via Università 100, 80055 Portici, Italy., Lombardi N; Department of Agricultural Sciences, University of Naples Federico II, Via Università 100, 80055 Portici, Italy.; BAT Center-Interuniversity Center for Studies on Bioinspired Agro-Environmental Technology, University of Naples Federico II, Via Università 100, 80055 Portici, Italy., Marra R; Department of Agricultural Sciences, University of Naples Federico II, Via Università 100, 80055 Portici, Italy.; BAT Center-Interuniversity Center for Studies on Bioinspired Agro-Environmental Technology, University of Naples Federico II, Via Università 100, 80055 Portici, Italy., Balestrieri A; Department of Animal Health, Istituto Zooprofilattico Sperimentale del Mezzogiorno, Via della Salute 2, 80055 Portici, Italy., Ritieni A; Department of Pharmacy, University of Naples Federico II, Via Domenico Montesano 49, 80131 Naples, Italy., Woo SL; Department of Pharmacy, University of Naples Federico II, Via Domenico Montesano 49, 80131 Naples, Italy.; BAT Center-Interuniversity Center for Studies on Bioinspired Agro-Environmental Technology, University of Naples Federico II, Via Università 100, 80055 Portici, Italy., Vinale F; BAT Center-Interuniversity Center for Studies on Bioinspired Agro-Environmental Technology, University of Naples Federico II, Via Università 100, 80055 Portici, Italy.; Department of Veterinary Medicine and Animal Productions, University of Naples Federico II, Via Federico Delpino 1, 80138 Naples, Italy.
Jazyk: angličtina
Zdroj: Molecules (Basel, Switzerland) [Molecules] 2022 Jun 20; Vol. 27 (12). Date of Electronic Publication: 2022 Jun 20.
DOI: 10.3390/molecules27123959
Abstrakt: The contamination of agricultural products with mycotoxins causes risks to animal and human health and severe economic losses. Mycotoxicoses can be reduced by preventing fungal infection using chemical and biological approaches. The chemical strategies can release toxic molecules; therefore, strategies for biological control are being evaluated, such as using nontoxic fungi and their metabolites. This work evaluated the effect of exoenzymes produced by the beneficial fungus Trichoderma afroharzianum strain T22 in degrading Aflatoxin B1 (AFB1) and Ochratoxin A (OTA). The ability of Trichoderma to produce hydrolases was stimulated by using different inducing substrates. The highest AFB1 and OTA degradation activity was obtained using a medium containing lyophilized mushrooms and crude fiber. The T. afroharzianum T22's ability to reduce mycotoxins may be attributed to peroxidase enzymes. This study showed that T. afroharzianum strain T22 or its peroxidase supplementation could represent a sustainable strategy for the degradation of AFB1 and OTA in feed and food products.
Databáze: MEDLINE
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