| Autor: |
Trung NV; Hanoi Medical University, Hanoi 100000, Vietnam.; Pasteur Institute in Ho Chi Minh City, Ho Chi Minh City 700000, Vietnam., Hoi LT; Hanoi Medical University, Hanoi 100000, Vietnam., Hoa TM; Hanoi Medical University, Hanoi 100000, Vietnam., Huong DT; Hanoi Medical University, Hanoi 100000, Vietnam., Huyen MT; Hanoi Medical University, Hanoi 100000, Vietnam., Tien VQ; Hanoi Medical University, Hanoi 100000, Vietnam., Mai DTT; Hanoi Medical University, Hanoi 100000, Vietnam., Ha NTT; Hanoi University of Public Health, Hanoi 100000, Vietnam., Kinh NV; National Hospital for Tropical Diseases, Hanoi 100000, Vietnam., Farris CM; Viral and Rickettsial Diseases Department, Naval Medical Research Center, Silver Spring, MD 20910, USA., Richards AL; Viral and Rickettsial Diseases Department, Naval Medical Research Center, Silver Spring, MD 20910, USA.; Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA. |
| Abstrakt: |
In Vietnam, the public health burden of rickettsial infections continues to be underestimated due to knowledge gaps in the epidemiology of these diseases. We conducted a systematic study among 27 hospitals from 26 provinces in eight ecological regions throughout Vietnam to investigate the prevalence, distribution, and clinical characteristics of rickettsial diseases. We recruited 1834 patients in the study from April 2018 to October 2019. The findings showed that rickettsial diseases were common among undifferentiated febrile patients, with 564 (30.8%) patients positive by qPCR for scrub typhus, murine typhus or spotted fever. Scrub typhus (484, 85.8%) was the most common rickettsial disease, followed by murine typhus (67, 11.9%) and spotted fever (10, 1.8%). Rickettsial diseases were widely distributed in all regions of Vietnam and presented with nonspecific clinical manifestations. |
