The Duration of Stone Disease and the Impact of a Stone Event on Patients' Quality of Life.

Autor: Raizenne BL; Division of Urology, Centre Hospitalier de l'Université de Montréal, Montréal, Canada., Deyirmendjian C; Faculty of Medicine, Université de Montréal, Montréal, Canada., Bechis SK; Department of Urology, University of California San Diego, San Diego, California, USA., Sur RL; Department of Urology, University of California San Diego, San Diego, California, USA., Nakada SY; Department of Urology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA., Antonelli JA; Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas, USA., Streeper NM; Division of Urology, Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA., Sivalingam S; Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, Ohio, USA., Viprakasit DP; Department of Urology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA., Averch TD; Department of Urology, Palmetto Health USC Medical Group, Columbia, South Carolina, USA., Landman J; University of California Irvine School of Medicine, Orange, California, USA., Chi T; Department of Urology, University of California San Francisco, San Francisco, California, USA., Pais VM; Urology Section, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire, USA., Chew BH; Department of Urologic Sciences, University of British Columbia, Vancouver, Canada., Bird VG; Department of Urology, University of Florida College of Medicine, Gainesville, Florida, USA., Andonian S; Division of Urology, McGill University Health Centre, Montreal, Canada., Canvasser NE; Department of Urology, University of California Davis, Sacramento, California, USA., Harper JD; Department of Urology, University of Washington, Seattle, Washington, USA., Penniston KL; Department of Urology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA., Bhojani N; Division of Urology, Centre Hospitalier de l'Université de Montréal, Montréal, Canada.
Jazyk: angličtina
Zdroj: Journal of endourology [J Endourol] 2022 Oct; Vol. 36 (10), pp. 1371-1376. Date of Electronic Publication: 2022 Aug 17.
DOI: 10.1089/end.2021.0897
Abstrakt: Introduction: With a 5-year stone recurrence rate of 30% to 50%, kidney stone formers are subject to significant morbidity that negatively impacts their health-related quality of life (HRQOL). We sought to determine the impact of age at kidney stone onset, duration of stone disease, and kidney stone event (surgery or stone passage) on HRQOL of individual patients by querying the validated and prospectively collected Wisconsin Stone Quality of Life (WISQOL) database. Patients and Methods: Cross-sectional data were obtained from a total of 2438 kidney stone formers from 14 institutions in North America who completed the WISQOL questionnaire during the period from 2014 to 2019. The 28-question survey has a 1- to 5-point scale for each item (total score range 0-140). Multivariable linear regression models assessed the impact of age at kidney stone onset, duration of stone disease, and time since most recent surgery or stone passage on HRQOL. Results: Of 2438 patients, older age at kidney stone onset and longer duration of disease were both independent predictors of better WISQOL scores ( β  = 0.33 points/year; confidence interval [CI] 0.17-0.49; p  < 0.001; and β  = 0.50 points/year; CI 0.32-0.68; p  < 0.001, respectively). Of 1376 patients who underwent surgery between 2010 and 2019, longer time since most recent surgery was an independent predictor of better WISQOL scores ( β  = 2.28 points/year; CI: 1.47-3.10; p  = <0.001). Of 1027 patients with spontaneous stone passage occurring between 2010 and 2019, longer time since most recent stone passage was an independent predictor of better WISQOL scores ( β  = 1.59 points/year; CI: 0.59-2.59; p  = <0.05). Conclusions: Our study demonstrates that older age at onset, longer duration of disease, and longer time since most recent surgery or stone passage were independent predictors of better HRQOL in kidney stone formers. Results of future studies that focus on optimizing stone-related modifiable risk factors to decrease the number of recurrent stone episodes and thus the need for recurrent surgeries will be essential.
Databáze: MEDLINE
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