Intra-articular corticosteroids associated with increased risk of total hip arthroplasty at 5 years.
| Autor: | Angotti ML; Midwest Orthopaedics at Rush LLC, Chicago, IL, USA., Burnett RA; Midwest Orthopaedics at Rush LLC, Chicago, IL, USA., Khalid S; Midwest Orthopaedics at Rush LLC, Chicago, IL, USA., Terhune EB; Midwest Orthopaedics at Rush LLC, Chicago, IL, USA., Della Valle CJ; Midwest Orthopaedics at Rush LLC, Chicago, IL, USA. |
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| Jazyk: | angličtina |
| Zdroj: | Hip international : the journal of clinical and experimental research on hip pathology and therapy [Hip Int] 2023 Sep; Vol. 33 (5), pp. 800-805. Date of Electronic Publication: 2022 Jun 19. |
| DOI: | 10.1177/11207000221107225 |
| Abstrakt: | Background: Intra-articular corticosteroid injections are commonly administered for hip pain. However, guidelines are conflicting on their efficacy, particularly in patients without arthritis. This study assessed for an association of corticosteroid injections and the incidence of total hip arthroplasty at 5 years. Methods: Patients with a diagnosis of hip pain without femoroacetabular osteoarthritis who were administered an intra-articular corticosteroid injection of the hip within a 2-year period were identified from the Mariner PearlDiver database. Patient were matched to patients with a diagnosis of hip pain who did not receive an injection. 5-year incidence of total hip arthroplasty was compared between matched patients who received an intra-articular corticosteroid injection and those who did not. Results: 2,540,154 patients diagnosed with hip pain without femoroacetabular arthritis were identified. 25,073 (0.9%) patients received a corticosteroid injection and were matched to an equal number of control patients. The incidence of total hip arthroplasty (THA) at 5-year-follow up was significantly higher for the corticosteroid cohort compared to controls (1.1% vs. 0.5%; p < 0.001). The incidence and risk of THA increased along with number of injections (1 injection: 0.8%, OR 1.37; 95% CI, 1.34-1.42; p < 0.001, 2 injections: 1.1%; OR 1.45; CI, 1.40-1.50; p < 0.001, ⩾3 injections: 1.5%; OR 1.48; CI, 1.40-1.56; p < 0.001). Conclusions: There may be a dose-dependent association of corticosteroid injections and a greater risk of total hip arthroplasty at 5 years. These results along with the conflicting guidelines on the efficacy of intra-articular steroids for hip pain should prompt physicians to consider osteoarthritis progression that may occur in the setting of corticosteroid injections in non-arthritic hips. |
| Databáze: | MEDLINE |
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